PRE-HOSPITAL THROMBOLYSIS IN KRASNOYARSK: RESULTS OF A RETROSPECTIVE COMPARATIVE STUDY
Aim. To compare the safety and efficacy of pre-hospital thrombolysis with tenecteplase and hospital thrombolysis with alteplase. Material and Methods. Pre-hospital thrombolytic therapy with tenecteplase (n=15) and hospital thrombolysis with alteplaza (n ...
S. A. Skripkin +4 more
doaj +1 more source
Effects of thrombolysis on outcomes of patients with deep venous thrombosis: An updated meta-analysis. [PDF]
BACKGROUND:Small randomized controlled studies and meta-analyses have shown that thrombolysis, especially catheter-directed thrombolysis, can reduce the incidence of post-thrombotic syndrome (PTS).
Zhenhua Xing +3 more
doaj +1 more source
Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila +5 more
core +2 more sources
Tenecteplase Thrombolysis for Acute Ischemic Stroke.
Tenecteplase is a fibrinolytic drug with higher fibrin specificity and longer half-life than the standard stroke thrombolytic, alteplase, permitting the convenience of single bolus administration.
S. Warach, A. Dula, T. Milling
semanticscholar +1 more source
Pulmonary embolism is a life-threatening condition treated with anticoagulation and systemic thrombolysis when appropriate. In patients with contraindications to thrombolysis, catheter-directed thrombolysis may be considered.
Steve M. Nelson, MD, Steven H. Craig, MD
doaj +1 more source
Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent +28 more
core +5 more sources
Stroke with unknown time of symptom onset: baseline clinical and magnetic resonance imaging data of the first thousand patients in WAKE-UP (efficacy and safety of mri-based thrombolysis in wake-up stroke: a randomized, doubleblind, placebo-controlled trial) [PDF]
Background and Purpose—We describe clinical and magnetic resonance imaging (MRI) characteristics of stroke patients with unknown time of symptom onset potentially eligible for thrombolysis from a large prospective cohort.
Boutitie, Florent +18 more
core +2 more sources
Background: Although intravenous (IV) thrombolysis is an effective treatment for patients with acute ischemic stroke (AIS), it remains underused by neurologists worldwide. This study assessed the knowledge and attitudes toward IV thrombolysis in patients
Fatimah Ali Alharbi +3 more
doaj +1 more source
Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith +6 more
core +2 more sources
Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register [PDF]
Purpose: Beyond intravenous thrombolysis, evidence is lacking on acute treatment of minor stroke caused by large artery occlusion. To identify candidates for additional endovascular therapy, we aimed to determine the frequency of non-haemorrhagic ...
Ahmed, Niaz +11 more
core +1 more source

