Results 51 to 60 of about 198,691 (330)

Hurdles in stroke thrombolysis: Experience from 100 consecutive ischemic stroke patients

Annals of Indian Academy of Neurology, 2015
Background: Acute management of ischemic stroke involves thrombolysis within 4.5 h. For a successful outcome, early recognition of stroke, transportation to the hospital emergency department immediately after stroke, timely imaging, proper diagnosis, and
Sagar Badachi, Thomas Mathew, Arvind Prabhu, Raghunandan Nadig, Gosala R. K. Sarma   +4 more
doaj   +1 more source

Clinical characteristics of unknown symptom onset stroke patients with and without diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch [PDF]

, 2017
Background: Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) mismatch was suggested to identify stroke patients with unknown time of symptom onset likely to be within the time window for thrombolysis. Aims: We aimed
Boutitie, Florent, Cheng, Bastian, Cho, Tae-Hee, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B., Fiehler, Jens, Ford, Ian, Galinovic, Ivana, Gerloff, Christian, Lemmens, Robin, Muir, Keith W., Nighoghossian, Norbert, Pedraza, Salvador, Puig, Josep, Roy, Pascal, Simonsen, Claus Z., Thijs, Vincent, Thomalla, Götz   +18 more
core   +2 more sources

Thrombolysis for Central Retinal Artery Occlusion in 2020: Time Is Vision!

Journal of neuro-ophthalmology, 2020
BACKGROUND Acute nonarteritic central retinal artery occlusion (CRAO) is an eye stroke with poor visual prognosis and no proven effective therapies. Given advances in acute stroke care, thrombolysis in CRAO merits critical re-examination.
O. Dumitrascu, N. Newman, V. Biousse
semanticscholar   +1 more source

The Association of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio With Post-Thrombolysis Early Neurological Outcomes in Patients With Acute Ischemic Stroke

, 2020
Background and Purpose: To investigate the association of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) with post-thrombolysis early neurological outcomes including early neurological improvement
Pengyu Gong, Yukai Liu, Yachi Gong, Gang Chen, Xiaohao Zhang, Siyu Wang, Feng Zhou, Rui Duan, Wenxiu Chen, Ting Huang, Meng Wang, Q. Deng, Hongchao Shi, Junshan Zhou, Teng Jiang, Yingdong Zhang   +15 more
semanticscholar   +1 more source

Time cost of a nonclosing intravenous thrombolysis service for acute ischemic stroke

Journal of the Formosan Medical Association, 2015
Background/Purpose: Intravenous thrombolysis for ischemic stroke saves societal costs. The aim of this study was to investigate the cost burden that hospitals may shoulder.
Mu-Chien Sun, Pi-Ju Hsiao
doaj   +1 more source

Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]

, 2008
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Ahmed, Niaz, Aichner, Franz, Bluhmki, Erich, Davalos, Antoni, Eriksson, Niclas, Erilä, Terttu, Ford, Gary A, Grond, Martin, Hacke, Werner, Hennerici, Michael G, Kaste, Markku, Köhrmann, Martin, Larrue, Vincent, Lees, Kennedy R, Machnig, Thomas, Peeters, André, Roine, Risto O, Toni, Danilo, Vanhooren, Geert, Wahlgren, Nils   +19 more
core   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Relationship of left ventricular outflow tract velocity time integral to treatment strategy in submassive and massive pulmonary embolism

Pulmonary Circulation, 2020
Pulmonary embolism is associated with high rates of mortality and morbidity. It is important to understand direct comparisons of current interventions to differentiate favorable outcomes and complications.
David Antoine, Taylor Chuich, Ruben Mylvaganam, Chris Malaisrie, Benjamin Freed, Michael Cuttica, Daniel Schimmel   +6 more
doaj   +1 more source

No space Left for Intravenous thrombolysis in acute stroke [PDF]

, 2016
Recent successful clinical trials of endovascular thrombectomy for large artery ischaemic stroke have established the value of this treatment modality as an adjunct to intravenous thrombolysis, not as an alternative: thrombectomy delivery was undertaken ...
Muir, Keith
core   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source