Results 31 to 40 of about 36,142 (215)
The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes [PDF]
, 2016 Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce ...
Brunel, Helena +7 more
core +4 more sources
A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
Research and Practice in Thrombosis and Haemostasis, 2022 Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis
Thomas G. Deloughery +4 more
doaj +1 more source
Hormone replacement therapy [PDF]
, 2012 Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core +2 more sources
The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia
Balkan Journal of Medical Genetics, 2014 Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from
Aradjanski M. +6 more
doaj +1 more source
Blood Advances, 2017 : Routine testing for inherited and acquired thrombophilia defects is frequently performed in pediatric patients with thromboembolic events (TEEs). No consensus guidelines exist regarding the timing of testing or the type of patients to be tested.
Chakri Gavva +2 more
doaj +1 more source
Thrombosis journal, 2006 Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. The predisposition to form clots can arise from genetic factors, acquired changes in the clotting mechanism, or, more commonly, an interaction ...
Dickerman Joseph D, Khan Salwa
openaire +3 more sources
Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]
, 2018 It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P +5 more
core +1 more source
The Assessment of Thromboembolism Risk in Postbariatric Patient: Our Experience in 936 Patients [PDF]
, 2016 open3openTanzillo, Giuseppe; Vindigni, Vincenzo; Bassetto, FrancoTanzillo, Giuseppe; Vindigni, Vincenzo; Bassetto ...
Bassetto, Franco +2 more
core +1 more source
Whole-exome sequencing in evaluation of patients with venous thromboembolism
Blood Advances, 2017 : Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, protein S, or ...
Eun-Ju Lee +25 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley +1 more source