Results 41 to 50 of about 20,101 (185)
Management of thrombophilia [PDF]
It is now possible to identify acquired and hereditary risk factors in a substantial percentage of patients presenting with a venous thrombotic event. Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia.
openaire +2 more sources
Prevalence of hereditary thrombophilia among Egyptian children with portal vein thrombosis
Background Portal vein thrombosis (PVT) is an important cause of portal hypertension in the pediatric age group with high morbidity rates due to its main complication—the upper gastrointestinal varices and hypersplenism.
Iman Mohamed Talaat +6 more
doaj +1 more source
Introduction: In Denmark, 10 % of new-borns are being conceived with the aid of medically assisted reproduction (MAR). MAR can imply induction of high levels of oestradiol, which in turn leads to increased coagulation activity, decreased natural ...
Jesper Strandberg +5 more
doaj +1 more source
Clinicopathological phenotypes of singleton stillbirth: A retrospective cohort study
Clinical information, description of placenta, and umbilical cord were reviewed, and microscopic slides re‐evaluated according to the Amsterdam Consensus. Stillbirths with maternal vascular malperfusion often had signs of high‐risk pregnancy, unlike stillbirths with villitis of unknown etiology, fetal vascular malperfusion, and umbilical cord at risk ...
Ragnheidur I. Bjarnadottir +5 more
wiley +1 more source
Laboratory Investigation of Thrombophilia [PDF]
Abstract Until recently, laboratory diagnosis of thrombophilia was based on investigation of the plasmatic anticoagulant pathways to detect antithrombin, protein C, and protein S deficiencies and on the search for dysfibrinogenemia and anti-phospholipid antibodies/lupus anticoagulants.
A. Tripodi, P. M. Mannucci
openaire +3 more sources
Thromboembolism (TE) is a complex disease caused by various acquired and inherited factors. The common mutations; factor V Leiden G1691A (FVL G1691A), prothrombin G20210A (PTG20210A), and methylene tetrahydrofolate reductase C677T (MTHFR C677T) are ...
Ali Ibrahim Mohammed MD, FICMS +3 more
doaj +1 more source
ABSTRACT Aim Childhood ischemic stroke is rare but causes substantial long‐term morbidity, and its heterogeneous aetiology complicates timely diagnosis and management. Methods We conducted a retrospective population‐based observational study using hospital data and chart review to describe diagnostics, treatment and outcomes of ischemic stroke in ...
Jussi V. Leinonen +8 more
wiley +1 more source
Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. The predisposition to form clots can arise from genetic factors, acquired changes in the clotting mechanism, or, more commonly, an interaction ...
Dickerman Joseph D, Khan Salwa
openaire +3 more sources
Postpartum maternal thrombophilia workup value in pregnancies with severe small for gestational age
Introduction In the absence of prenatal etiology explaining small for gestational age (SGA), a blood workup may be performed postpartum to look for maternal thrombophilia if a newborn is confirmed to be growth‐restricted at birth.
Maëlig Abgral +6 more
doaj +1 more source

