Results 31 to 40 of about 27,558 (226)
Journal of Aging Research, 2011 Introduction. Advances in hemophilia care and treatment have led to increases in the life expectancy among hemophiliacs. As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen ...
Aroub A. Khleif +3 more
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BMJ Open, 2022 Objective There are numerous studies reporting a disproportionally high prevalence of thrombophilia in women with a history of recurrent miscarriage (RM), which has led to overdiagnosis and treatment without an improvement in clinical outcomes.
Hassan Shehata +7 more
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Features of pregnancy course in patients with thrombophilia and abnormal placenta location
Акушерство, гинекология и репродукция, 2023 Aim: to identify inherited and acquired thrombophilia as well as features of pregnancy course in women with abnormal placenta location.Materials and Methods.
V. B. Zubenko, A. I. Lovkova
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Thrombophilia identified as a risk factor for thrombogenesis in cancer patients
Акушерство, гинекология и репродукция, 2021 Aim: to assess a rate and range of genetic and acquired thrombophilia in onco-gynecologic patients with ovarian cancer, uterine corpus cancer and cervical cancer.Materials and Мethods.
A. V. Vorobev +4 more
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Management of thrombophilia [PDF]
Journal of Thrombosis and Haemostasis, 2003 It is now possible to identify acquired and hereditary risk factors in a substantial percentage of patients presenting with a venous thrombotic event. Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia.
openaire +2 more sources
TH OpenA rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin.
Émile Moura Coelho da Silva +2 more
doaj +1 more source
, 2021 The number of thrombophilia investigations has been steadily increasing over the past decade. However, it is debatable to what extent treatment of thromboembolic events is further qualified by thrombophilia investigations.
Hvas, Anne-Mette +2 more
core +1 more source
Research and Practice in Thrombosis and Haemostasis, 2021 Direct oral anticoagulants (DOACs) are widely used in several indications, but data on their efficacy and safety in individuals affected by severe inherited thrombophilia, yet without any personal history of thrombosis, is lacking.
Evelien Krumb, Cedric Hermans
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Whole-exome sequencing in evaluation of patients with venous thromboembolism
Blood Advances, 2017 : Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, protein S, or ...
Eun-Ju Lee +25 more
doaj +1 more source
A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
Research and Practice in Thrombosis and Haemostasis, 2022 Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis
Thomas G. Deloughery +4 more
doaj +1 more source