Results 21 to 30 of about 20,101 (185)

Thrombophilia and Hypercoagulability [PDF]

Medical Principles and Practice, 2009
This is a review of less well-known aspects of thrombophilia and hypercoagulability as they relate to thrombosis. Thrombosis is an abnormal fibrin clot that develops in circulating blood with clinical symptoms of one or more arterial and/or venous obstructions exclusively identified by imaging techniques.
openaire   +2 more sources

Mechanisms of thrombophilia [PDF]

Thrombosis and Haemostasis, 2007
Editorial.-- El pdf es la versión post-print.
openaire   +3 more sources

Whole-exome sequencing in evaluation of patients with venous thromboembolism

Blood Advances, 2017
: Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, protein S, or ...
Eun-Ju Lee, Daniel J. Dykas, Andrew D. Leavitt, Rodney M. Camire, Eduard Ebberink, Pablo García de Frutos, Kavitha Gnanasambandan, Sean X. Gu, James A. Huntington, Steven R. Lentz, Koen Mertens, Christopher R. Parish, Alireza R. Rezaie, Peter P. Sayeski, Caroline Cromwell, Noffar Bar, Stephanie Halene, Natalia Neparidze, Terri L. Parker, Adrienne J. Burns, Anne Dumont, Xiaopan Yao, Cassius Iyad Ochoa Chaar, Jean M. Connors, Allen E. Bale, Alfred Ian Lee   +25 more
doaj   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia

Balkan Journal of Medical Genetics, 2014
Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from
Aradjanski M., Djordjevic V., Pruner I., Tomic B., Gvozdenov M., Kovac M., Radojkovic D.   +6 more
doaj   +1 more source

A clinical audit of thrombophilia testing in pediatric patients with acute thromboembolic events: impact on management

Blood Advances, 2017
: Routine testing for inherited and acquired thrombophilia defects is frequently performed in pediatric patients with thromboembolic events (TEEs). No consensus guidelines exist regarding the timing of testing or the type of patients to be tested.
Chakri Gavva, Ravindra Sarode, Ayesha Zia   +2 more
doaj   +1 more source

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Prevalence and factors associated with high-risk thrombophilia: a single-center cross-sectional study of 3550 patients at a tertiary Thrombosis Centre in Switzerland

Research and Practice in Thrombosis and Haemostasis
Background: Thrombophilia testing remains controversial, with no standardized recommendations across patient populations. Objectives: Given the clinical significance of high-risk thrombophilia (homozygous factor V Leiden or prothrombin G20210A mutations,
Shabnam Najaf Zadeh, Fabienne Schmidli, Katarzyna Aleksandra Jalowiec, Tobias Tritschler, Yan Xu, Alan Haynes, Grégoire Le Gal, Anne Angelillo-Scherrer, Kristina Vrotniakaite-Bajerciene   +8 more
doaj   +1 more source