Results 11 to 20 of about 19,931 (150)

Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care

Journal of Aging Research, 2011
Introduction. Advances in hemophilia care and treatment have led to increases in the life expectancy among hemophiliacs. As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen ...
Aroub A. Khleif, Nidra Rodriguez, Deborah Brown, Miguel A. Escobar   +3 more
doaj   +1 more source

Effects of Obesity and Thrombophilia on the Risk of Abortion in Women Undergoing In Vitro Fertilization

Frontiers in Endocrinology, 2020
IntroductionObesity is associated with a higher risk of abortion in women undergoing in vitro fertilization (IVF). Whether thrombophilia amplifies this risk is currently unclear.
Matteo Candeloro, Marcello Di Nisio, Marcello Di Nisio, Adalisa Ponzano, Gian Mario Tiboni, Nicola Potere, Marco Tana, Anne W. S. Rutjes, Ettore Porreca   +8 more
doaj   +1 more source

Thrombophilia screening in women with recurrent first trimester miscarriage: is it time to stop testing? – a cohort study and systematic review of the literature

BMJ Open, 2022
Objective There are numerous studies reporting a disproportionally high prevalence of thrombophilia in women with a history of recurrent miscarriage (RM), which has led to overdiagnosis and treatment without an improvement in clinical outcomes.
Hassan Shehata, Ranjit Akolekar, Amanda Ali, Mariane Silva-Edge, Shahla Haroon, Abdullatif Elfituri, Radhika Viswanatha, Haider Jan   +7 more
doaj   +1 more source

Thrombophilia identified as a risk factor for thrombogenesis in cancer patients

Акушерство, гинекология и репродукция, 2021
Aim: to assess a rate and range of genetic and acquired thrombophilia in onco-gynecologic patients with ovarian cancer, uterine corpus cancer and cervical cancer.Materials and Мethods.
A. V. Vorobev, A. D. Makatsariya, V. O. Bitsadze, A. G. Solopova, D. A. Ponomarev   +4 more
doaj   +1 more source

Thrombophilia and pregnancy

Reproductive Biology and Endocrinology, 2003
Pregnancy is hypercoagulable state. The field of thrombophilia; the tendency to thrombosis, has been developed rapidly and has been linked to many aspects of pregnancy.
Kupferminc Michael J
doaj   +1 more source

Features of pregnancy course in patients with thrombophilia and abnormal placenta location

Акушерство, гинекология и репродукция, 2023
Aim: to identify inherited and acquired thrombophilia as well as features of pregnancy course in women with abnormal placenta location.Materials and Methods.
V. B. Zubenko, A. I. Lovkova
doaj   +1 more source

Primary prophylaxis of venous thromboembolic disease with direct oral anticoagulants in patients with severe inherited thrombophilia

Research and Practice in Thrombosis and Haemostasis, 2021
Direct oral anticoagulants (DOACs) are widely used in several indications, but data on their efficacy and safety in individuals affected by severe inherited thrombophilia, yet without any personal history of thrombosis, is lacking.
Evelien Krumb, Cedric Hermans
doaj   +1 more source

A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing

Research and Practice in Thrombosis and Haemostasis, 2022
Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis
Thomas G. Deloughery, Beverley J. Hunt, Geoffrey D. Barnes, Jean M. Connors, The WTD Steering Committee   +4 more
doaj   +1 more source

Whole-exome sequencing in evaluation of patients with venous thromboembolism

Blood Advances, 2017
: Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, protein S, or ...
Eun-Ju Lee, Daniel J. Dykas, Andrew D. Leavitt, Rodney M. Camire, Eduard Ebberink, Pablo García de Frutos, Kavitha Gnanasambandan, Sean X. Gu, James A. Huntington, Steven R. Lentz, Koen Mertens, Christopher R. Parish, Alireza R. Rezaie, Peter P. Sayeski, Caroline Cromwell, Noffar Bar, Stephanie Halene, Natalia Neparidze, Terri L. Parker, Adrienne J. Burns, Anne Dumont, Xiaopan Yao, Cassius Iyad Ochoa Chaar, Jean M. Connors, Allen E. Bale, Alfred Ian Lee   +25 more
doaj   +1 more source

The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia

Balkan Journal of Medical Genetics, 2014
Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from
Aradjanski M., Djordjevic V., Pruner I., Tomic B., Gvozdenov M., Kovac M., Radojkovic D.   +6 more
doaj   +1 more source