Results 111 to 120 of about 86,967 (270)
Transfusion, EarlyView.Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa +9 more
wiley +1 more source
Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy
Transfusion, EarlyView.Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna +7 more
wiley +1 more source
Transfusion, EarlyView.Abstract Background RhD mismatched transfusions in RhD negative women have the potential to impact future pregnancies through alloimmunization and development of hemolytic disease of the fetus and newborn (HDFN). As use of RhD positive emergency‐release blood products in pediatric trauma has increased, it has become clear that a significant ...
Kirea Lange +7 more
wiley +1 more source
Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma
Transfusion, EarlyView.Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan +4 more
wiley +1 more source
Transfusion, EarlyView.Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden +6 more
wiley +1 more source
A ruptured vulvar labial artery pseudoaneurysm causes a secondary postpartum hemorrhage: A case report. [PDF]
, 2020 Background:Postpartum hemorrhage is the most common cause of maternal morbidity in the United States. However, secondary postpartum hemorrhage is rare and includes pseudoaneurysms, which represent only 3.3% of all cases of secondary postpartum hemorrhage.
Lane, Felicia +3 more
core
The impact of rapid infusers on the hemostatic potential of cryoprecipitate products
Transfusion, EarlyView.Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis +7 more
wiley +1 more source
Combined deficiency of factor V and factor VIII in a pediatric patient: a case report
Journal of Medical Case ReportsBackground Combined deficiency of factors V and VIII is a rare autosomal recessive disorder associated with an increased risk of bleeding. We present an unusual case of a 7-year-old Moroccan child with no history of consanguinity who was hospitalized ...
Yasmine Bendarkawi +4 more
doaj +1 more source