Results 141 to 150 of about 111,198 (373)
Safety and Use of Eptacog Beta 225 µg/kg in Patients With Haemophilia A or B With Inhibitors
Introduction Eptacog beta is an activated recombinant human factor VII bypassing agent approved for treating bleeding episodes (BEs) in patients aged ≥12 years with haemophilia A or B with inhibitors. Two initial dose regimens (IDRs) of either 75 or 225 µg/kg, followed by 75 µg/kg, are approved.
Manuel Carcao+7 more
wiley +1 more source
Factor VII Padua 2: another factor VII abnormality with defective ox brain thromboplastin activation and a complex hereditary pattern [PDF]
Antonio Girolami+3 more
openalex +1 more source
Investigation of sensitivity for coagulation factor deficiency in APTT and PT : how to perform it? [PDF]
Devreese, Katrien+2 more
core +1 more source
Estimating the Factor VIII‐Equivalent Activity of Emicizumab Using Global Assays of Haemostasis
ABSTRACT Background Emicizumab is a bispecific monoclonal antibody mimicking factor (F) VIII activity and an effective therapy for prophylaxis in people with haemophilia A (PWHA). The FVIII‐equivalent activity (FVIIIeq) of emicizumab remains unknown. Objectives To estimate FVIIIeq of emicizumab using global assays of haemostasis.
Daniel Kraemmer+6 more
wiley +1 more source
Phospholipase C from Bacillus cereus and Its Use in Studies of Tissue Thromboplastin [PDF]
Anne‐Brit Otnæss+3 more
openalex +1 more source
Abstract Aim Antithrombin (AT), a plasma protein with anticoagulant properties, has a long‐standing medical history, primarily for treatment of congenital AT deficiency. Accumulated clinical experiences suggest AT is a potential anticoagulant for thrombotic diseases. This study aimed to clarify the effectiveness, safety, and clinical significance of AT
Shoichi Matsutani+2 more
wiley +1 more source
The partial thromboplastin (cephalin) time test [PDF]
L. Poller, J M Thomson
openalex +1 more source
Risk Factors for Traumatic Lumbar Puncture in Children With ALL
Acta Paediatrica, EarlyView.
Sirkku Setänen+3 more
wiley +1 more source
Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani+2 more
wiley +1 more source