Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Influence of vitamin K antagonist treatment on activated partial thromboplastin time [PDF]
, 2015 A
Devreese, Katrien +2 more
core +2 more sources
Frontiers in Oncology, 2017 Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che +2 more
doaj +1 more source
Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]
, 2010 The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Braun, Jean-Pierre +5 more
core +1 more source
Timing and volume of fluid administration for patients with bleeding [PDF]
, 2003 Original article can be found at: http://www3.interscience.wiley.com Copyright John Wiley & Sons. ‘This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2003, Issue 3.
Bunn, Frances, Kwan, I., Roberts, I.
core +1 more source
Safety of Needle Electromyography in Critically Ill Patients [PDF]
, 2020 Introduction: To evaluate the safety of needle electromyography (EMG) in critically ill intensive care unit (ICU) patients who are on anticoagulants and have comorbidities that increase the risk of bleeding and infections.
Bollu, Pradeep +5 more
core +2 more sources
Clotting Phenomena at the Blood-Polymer Interface and Development of Blood Compatible Polymeric Surfaces [PDF]
, 1972 In the past two decades many attempts have been made to relate surface and interfacial parameters with the blood compatibility of polymeric surfaces. It is however doubtful if by a single parameter the behaviour of blood on a surface can be predicted ...
Bantjes, Adriaan
core +3 more sources
A comparison of two techniques of cell block preparation
Journal of Pathology of Nepal, 2019 Background: Cell block technique is a method of preparing cytological material so that it can be processed, sectioned, stained, and viewed as a histology section.
Anita Kasichhwa +2 more
doaj +1 more source
Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]
, 1989 Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ +5 more
core +1 more source
Hereditary factor XII deficiency in an adult patient: A case report
SAGE Open Medical Case Reports, 2022 Factor XII deficiency is a rare autosomal recessive health condition usually discovered incidentally during routine coagulation screening before surgery after investigating a prolongation of the activated partial thromboplastin time.
Rehab Y Al-Ansari +3 more
doaj +1 more source