Results 251 to 260 of about 86,919 (334)

Molecular Aspects of Rare Coagulation Factor Deficiencies. [PDF]

open access: yesCureus
Tourbih H   +4 more
europepmc   +1 more source

Therapeutic Plasma Exchange After Spontaneous Intracranial Hemorrhage for a Patient With Antiphospholipid Syndrome and Lupus Anticoagulant Hypoprothrombinemia

open access: yesJournal of Clinical Apheresis, Volume 40, Issue 5, October 2025.
ABSTRACT Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid antibodies (aPL), macro‐ and micro‐vascular thromboembolic complications. Lupus anticoagulant‐hypoprothrombinemia (LAHPS) may confound the diagnosis and management of bleeding. Catastrophic APS has a category 1 indication for therapeutic plasma exchange (TPE).
Joshua Nicholas   +4 more
wiley   +1 more source

A Multicenter, Open‐Label Study to Assess the Safety of Nebulized Tissue Plasminogen Activator for the Acute Treatment of Pediatric Plastic Bronchitis: The PLATyPuS Trial

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 677-687, October 2025.
ABSTRACT Introduction Pediatric plastic bronchitis (PB) is a rare complication of surgically palliated congenital heart disease (CHD). Fibrin casts obstruct airways and can cause respiratory distress. There are no therapeutics approved by the United States Food and Drug Administration to treat PB, but inhaled tissue plasminogen activator (tPA) has been
Kathleen A. Stringer   +10 more
wiley   +1 more source

Diffuse Alveolar Haemorrhage Complicated by Pulmonary Metastasis of Cardiac Angiosarcoma and Kasabach–Merritt Syndrome: A Case Report

open access: yesRespirology Case Reports, Volume 13, Issue 10, October 2025.
We report an exceptional case of cardiac angiosarcoma in which diffuse alveolar haemorrhage was caused by both pulmonary metastases and Kasabach–Merritt syndrome. Strategies to achieve transfusion‐independent haemostasis such as high PEEP may create an opportunity for prompt biopsy and facilitate timely initiation of definitive treatment.
Takuma Ikeda, Satoru Terada, Kazuo Endo
wiley   +1 more source

Prehospital Treatment With Dried Plasma in Patients With Major Bleeding—A Prospective Randomised Controlled Multicentre Trial: Statistical Analysis Protocol

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 9, October 2025.
ABSTRACT Background Major haemorrhage remains one of the most preventable causes of early death in prehospital care. While prehospital administration of plasma has shown potential to improve survival, logistical challenges limit its use outside hospitals. Dried plasma offers a practical solution, particularly in rural or remote environments.
G. Skallsjö   +3 more
wiley   +1 more source

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