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Activated partial thromboplastin time (APTT), partial thromboplastin time (PTT)

open access: yesActivated partial thromboplastin time (APTT), partial thromboplastin time (PTT)
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Activated Partial Thromboplastin Time

Methods in molecular biology, 2013
Activated partial thromboplastin time (APTT) is a commonly used coagulation assay that is easy to perform, is affordable, and is therefore performed in most coagulation laboratories, both clinical and research, worldwide. The APTT is based on the principle that in citrated plasma, the addition of a platelet substitute, factor XII activator, and CaCl2 ...
V. Ignjatovic
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Thromboplastin standards

Biologicals, 2010
The Prothrombin Time (PT) test is used for monitoring of treatment with Vitamin K-antagonists (VKA). The result of the PT test should be expressed as the International Normalized Ratio (INR). Calculation of INR is based on the availability of International Standards (IS) for thromboplastin and a calibration model. Calibration of a new PT test system is
A. M. van den Besselaar   +2 more
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Plasma Thromboplastin Antecedent

A.M.A. Archives of Internal Medicine, 1955
Until recently, male persons with a severe hemorrhagic diathesis characterized by (1) a prolonged clotting time, (2) normal Quick plasma prothrombin time, but (3) a poor prothrombin consumption were unhesitatingly diagnosed as suffering from classic hemophilia.
B, RAMOT, B, ANGELOPOULOS, K, SINGER
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Calibration of thromboplastins

Proceedings of the Royal Society of London. Series B: Biological Sciences, 1995
Anticoagulant therapy with coumarin drugs requires tests on the patient's blood to determine the dose rate for the drug. The tests involve measuring the effect of a preparation of a certain reagent, thromboplastin, in accelerating the clotting of the patient's blood.
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THROMBOPLASTIN REFERENCE PREPARATIONS

Scandinavian Journal of Haematology, 1980
The need for standardization of methods for the control of anticoagulant therapy was apparent 25 years ago. With the development of the ratio method for comparing the sensitivity of different thromboplastin preparations it became possible to equate the value obtained with one preparation in terms of the value which would be obtained with any other ...
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Thromboplastin Generation Test

JAMA: The Journal of the American Medical Association, 1967
In the classical theory of blood coagulation, it was postulated that prothrombin was converted to thrombin through the action of calcium and thromboplastin. It is now established that circulating blood contains no active thromboplastin but that thromboplastin is generated during coagulation.
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Thromboplastin generation by saliva

Oral Surgery, Oral Medicine, Oral Pathology, 1962
Abstract In order to determine directly whether saliva has any specific thromboplastic activity or whether its effect in accelerating blood coagulation is nonspecific, we compared saliva with commercial tissue thromboplastins in the following modified hematologic tests: 1. 1.
H C, DOKU, R G, TAYLOR
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Comparison of a Highly Sensitive Rabbit Brain Thromboplastin, Dade Thromboplastin FS, with a Human Brain Thromboplastin, Manchester Comparative Thromboplastin

1984
A few years ago, a field trial was carried out in which a large number of plasma samples (100 normals, 806 anticoagulated patients, as well as patients with deficiencies of the factors II, V, VII and X) were tested with a newly developed rabbit brain thromboplastin (Thromboplastin FS) and with Human Brain Thromboplastin prepared by Prof.
R. Spaethe, I. Shirley
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