Results 41 to 50 of about 60,582 (221)

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization

Advanced NanoBiomed Research, EarlyView.
A biomimetic vascular graft combining biofunctionalized PVA‐MA hydrogels with a MEW scaffold is developed for small‐diameter applications. Gel‐MA and Hep‐MA incorporation enhances endothelialization and hemocompatibility, respectively, targeting the acute biological responses.
Verena Kronberger, Shouyuan Jiang, Minh H. Ho, Jasneil Singh, Chung‐Wei (Roy) Hsu, Gabriella C. J. Lindberg, Khoon S. Lim, Tomasz Jungst, Anna Waterhouse   +8 more
wiley   +1 more source

Serum tissue factor as a biomarker for renal clear cell carcinoma

International Brazilian Journal of Urology
Purpose to determine the usefulness of serum TF as a potential marker for patients with clear cell RCC. Materials and Methods prospective study of 30 patients with clear cell RCC submitted to nephrectomy and 16 controls without clear cell RCC treated ...
Daniel D’Oliveira Silva, Jorge A. P. Noronha, Bartira E. Pinheiro da Costa, Pedro Caetano Edler Zandona, Gustavo F. Carvalhal   +4 more
doaj   +1 more source

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

PARTIAL THROMBOPLASTIN TIME CHANGES IN ASTHMA

Journal of Research in Medical Sciences, 2003
Study objective: To exam the effect of asthma on- coagulation pathway. Methods: Case control study with 73 asthmatic pagtients at different age. Results: We show that PIT in asthmatic patients is longer than in control group (P < 0.0001). We
A MIRALAEI, F AFSHINNIA
doaj  

Restrictive versus liberal fluid administration strategy (REFILL study) in postpartum hemorrhage and its effects on thromboelastometry (ROTEM®) values: a randomized, controlled trial

Journal of International Medical Research, 2023
Objective Current obstetric guidelines for postpartum hemorrhage (PPH) vary in fluid resuscitation management. This study aimed to evaluate the effect of fluid management on coagulation parameters in early PPH.
Pim B.B. Schol, Natascha de Lange, Yvonne Henskens, Luc J.M. Smits, Nicol A.C. Smeets, Hubertina C.J. Scheepers   +5 more
doaj   +1 more source

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source

Quantitative Model‐Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
Milvexian, an activated factor XI inhibitor, is being evaluated in the LIBREXIA phase III program for the prevention of thrombotic events, including in patients with atrial fibrillation (LIBREXIA AF). To guide the selection of a phase III dose regimen for LIBREXIA AF, two main approaches were used: (1) population pharmacokinetics and exposure–response ...
Wangda Zhou, Emily Bozenhardt, Gregory E. Alexander, Matthew L. Zierhut, Samira Merali, Antoinette Ajavon‐Hartmann, Peter Zannikos, Hyunmoon Back, EunYoung Suh, Navin Goyal, Mahesh N. Samtani, Alexei N. Plotnikov, Chandni Valiathan   +12 more
wiley   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source

Effect of Haemodialysis on Mean Prothrombin Time and Activated Partial Thromboplastin Time in Patients of End Stage Renal Disease

Journal of Rawalpindi Medical College, 2015
Background: To determine mean prothrombin time and activated partial thromboplastin time in patients of end stage renal disease having normal baseline coagulation parameters after hemodialysis.
Attika Khalid
doaj