Results 71 to 80 of about 7,460 (217)
Thrombocytosis as a prognostic marker in stage III and IV serous ovarian cancer. [PDF]
, 2014 OBJECTIVE: Thrombocytosis is an adverse prognostic factor in many types of cancer. We investigated if pre-treatment increased platelet counts provide prognostic information specifically in patients with stage III and IV serous ovarian cancer which is the
Digklia, A., Voutsadakis, I.A.
core +1 more source
Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions
Aging Cell, Volume 25, Issue 2, February 2026.Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki +3 more
wiley +1 more source
A recurrent translocation, t(3;11)(q21;q13), found in two distinct cases of acute myeloid leukemia [PDF]
, 1995 We report two cases of acute myeloid leukemia (M1 and M5B subtypes) with a similar translocation, t(3;11)(q21;q13).
Bengoechea, E. (Enrique) +5 more
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Clinical Case Reports, Volume 14, Issue 1, January 2026.Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff +2 more
wiley +1 more source
A megakaryocyte in the peripheral blood: evidence for pulmonary migration?
Frontiers in HematologyPulmonary megakaryocytes were first identified over a century ago, but their origin is still debated. Two rare images of circulating megakaryocytes are presented to illustrate this discussion: The first shows an intact megakaryocyte with abundant ...
Stephanie Juané Kennedy +1 more
doaj +1 more source
Effect of simvastatin on thrombopoiesis in porcine bone marrow
Journal of Veterinary Research, 2019 Introduction: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the ...
Snarska Anna +2 more
doaj +1 more source
Modern concepts of the platelet in health and disease [PDF]
, 1962 Thesis (M.D.)--Boston ...
Estes, J. Worth
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Health Science Reports, Volume 9, Issue 1, January 2026.ABSTRACT Introduction Thrombocytopenia, particularly immune thrombocytopenic purpura, is a prevalent hematological disorder characterized by low platelet counts, leading to increased bleeding risks. Genetic factors, including single nucleotide polymorphisms, are implicated in its pathogenesis.
Sorour Alizadeh Saadooni +6 more
wiley +1 more source
A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation
Platelets, 2018 Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand ...
M. Salzmann +9 more
doaj +1 more source
Calreticulin in Essential Thrombocythemia: StressINg OUT the Megakaryocyte Nucleus
Frontiers in Oncology, 2017 Calreticulin (CALR) is a multifaceted protein primarily involved in intracellular protein control processes. The identification of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis that are mutually exclusive with the JAK2 V617F ...
Francisco Jose Iborra +1 more
doaj +1 more source