Results 51 to 60 of about 30,205 (229)

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Technique for Lateral Opening Wedge Distal Femoral Osteotomy Using Patient‐Specific Instrumentation for Genu Valgum and Patellar Instability

Arthroscopy Techniques, EarlyView.
Abstract Recurrent lateral patellar instability poses a technical challenge to orthopaedic surgeons. Isolated soft‐tissue procedures through medial patellofemoral ligament reconstruction or lateral release show unacceptably high failure rates. Lateral opening wedge distal femoral osteotomy addresses underlying bony malalignment and reinforces the soft ...
Alexander P. Decilveo, Elan Karlin, Neil Patel, Allison Ariniello, George F. Rick Hatch   +4 more
wiley   +1 more source

Thromboprophylaxis in people hospitalized with COVID‐19: Assessing intermediate or standard doses in a retrospective cohort study

Research and Practice in Thrombosis and Haemostasis, 2022
Background and Objectives Current clinical guidelines recommend thromboprophylaxis for adults hospitalized with coronavirus disease 2019 (COVID‐19), yet it is unknown whether higher doses of thromboprophylaxis offer benefits beyond standard doses ...
Kathleen M. Andersen, Corey S. Joseph, Hemalkumar B. Mehta, Michael B. Streiff, Joshua F. Betz, Robert C. Bollinger Jr, Arielle M. Fisher, Amita Gupta, Charles F. LeMaistre, Matthew L. Robinson, Yanxun Xu, Derek K. Ng, G. Caleb Alexander, Brian T. Garibaldi   +13 more
doaj   +1 more source

Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study [PDF]

, 2016
Objective: To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum). Design: Cohort study.
Fleming, Kate M., Grainge, Matthew J., Ludvigsson, Jonas F., Nelson-Piercy, Catherine, Riley, Richard D., Stephansson, Olof, Sultan, Alyshah Abdul, Tata, Laila J., West, Joe   +8 more
core   +2 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

TropicALL study: Thromboprophylaxis in Children treated for Acute Lymphoblastic Leukemia with Low-molecular-weight heparin: a multicenter randomized controlled trial

BMC Pediatrics, 2017
Background Venous thromboembolism (VTE) is a common and severe complication during treatment of acute lymphoblastic leukemia (ALL). An important cause is the intensive use of asparaginase.
Irene L. M. Klaassen, Mandy N. Lauw, Marianne D. van de Wetering, Bart J. Biemond, Saskia Middeldorp, Floor C. H. Abbink, Marc Bierings, D. Maroeska M. W. te Loo, Rob Pieters, Inge M. van der Sluis, Wim J. E. Tissing, C. Michel Zwaan, C. Heleen van Ommen   +12 more
doaj   +1 more source

Improvement of Perioperative Management of Patients Undergoing Surgical Treatment for Hip Periprosthetic Joint Infection

Travmatologiâ i Ortopediâ Rossii, 2021
Two-stage revision arthroplasty in chronic hip periprosthetic joint infection cases is the “gold standard” treatment. First stage debridement leads to large intraoperative and drainage blood loss using standard protocols for thromboprophylaxis and ...
A. A. Kochish, S. A. Bozhkova, V. A. Artyukh, V. N. Liventsov, A. V. Afanas’ev, S. S. Toropov   +5 more
doaj   +1 more source

The effect of active toe movement (AToM) on calf pump function and deep vein thrombosis in patients with acute foot and ankle trauma treated with cast - a prospective randomized study [PDF]

, 2017
Background Patients with foot and ankle trauma treated with cast are advised to perform toe movements to prevent venous thromboembolism (VTE). Our aim was to determine the effect of active toe movement on asymptomatic deep vein thrombosis (DVT) and ...
Alikhan, Raza, Cleves, Andrew, Hickey, Benjamin A., Nokes, Leonard Derek Martin, Perera, Anthony, Pugh, Neil D.   +5 more
core   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source

Safety and efficacy of a new thromboprophylaxis regiment for total knee and total hip replacement: a retrospective cohort study in 265 patients

Patient Safety in Surgery, 2018
Background Venous thromboembolism (VTE) remains a significant complication following knee and hip arthroplasty. National and international guidelines recommend pharmacological and mechanical thromboprophylaxis following surgery, unless contraindicated ...
Mohammad Amre Fallaha, Sarkhell Radha, Sheena Patel   +2 more
doaj   +1 more source