Results 61 to 70 of about 29,753 (220)

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source

Preoperative versus postoperative initiation of thromboprophylaxis following major orthopedic surgery: safety and efficacy of postoperative administration supported by recent trials of new oral anticoagulants

Thrombosis Journal, 2011
In European countries, low-molecular-weight heparin is generally initiated preoperatively for thromboprophylaxis in hip or knee replacement surgery. The objective of this review is to compare pre- and postoperative thromboprophylaxis strategies using ...
Perka Carsten
doaj   +1 more source

Arterial complications, venous thromboembolism and deep venous thrombosis prophylaxis after anterior cruciate ligament reconstruction: A systematic review [PDF]

, 2016
AIM To summarize the current knowledge on vascular complications and deep venous thrombosis (DVT) prophylaxis after anterior cruciate ligament (ACL) reconstruction.
Janssen, D.M. (Daan Martijn), Janssen, R.P.A. (Rob), Reijman, M. (Max), van Mourik, J.B.A. (Jan Bernardus Antonius)   +3 more
core   +3 more sources

Comparable outcomes and early revision rates between restricted and unrestricted functional knee positioning in robotic‐assisted total knee arthroplasty for varus deformities ≥10°

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Functional knee positioning (FKPos) in total knee arthroplasty (TKA) optimises outcomes by balancing individual anatomical and soft tissue characteristics. Managing marked varus deformity presents challenges in achieving balance when tibial alignment is restricted to 3° of varus, necessitating either medial soft tissue release or ...
Christos Koutserimpas, Konstantinos Dretakis, Enejd Veizi, Nevzat Arıcan, Elvire Servien, Cécile Batailler, Sébastien Lustig   +6 more
wiley   +1 more source

Normal pregnancy is associated with an increase in thrombin generation from the very early stages of the first trimester [PDF]

, 2017
Background: Pregnancy is a hypercoagulable state associated with an increased risk of venous thrombosis, which begins during the first trimester, but the exact time of onset is unknown.
Bagot, C.N., Freeman, D.J., Jordan, F., Leishman, E., Onyiaodike, C.C.   +4 more
core   +1 more source

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri, Francesco Ferriani, Enrico Di Benedetto, Enrick Miani, Enrico Festa, Giovanni Balato, Stefano M. P. Rossi, Francesco Benazzo, Andrea Baldini   +8 more
wiley   +1 more source

Reduced postoperative inflammation and blood loss after robotic arm‐assisted unicompartmental compared with total knee arthroplasty: A propensity score‐matched analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic arm‐assisted unicompartmental knee arthroplasty (raUKA) offers potential advantages over robotic arm‐assisted total knee arthroplasty (raTKA), but its biological benefits remain unclear. Superior early recovery after raUKA may be related to reduced systemic inflammation and blood loss.
Dirk Müller, Florian Pohlig, Benjamin Schloßmacher, Vincent Lallinger, Michael T. Hirschmann, Rüdiger von Eisenhart‐Rothe, Igor Lazic   +6 more
wiley   +1 more source

What influences women’s decisions to participate in trials for prevention of venous thromboembolism during pregnancy and the puerperium: a qualitative study

BMC Pregnancy and Childbirth
Background Thromboprophlyaxis for the prevention of venous thromboembolism during pregnancy and the puerperium is widespread, but there is a lack of evidence on the risks and benefits of thromboprophylaxis within this population.
Fiona C Sampson, Sarah Davis, Maxine Kuczawski, Rosemary Carser, Beverley J Hunt, Steve Goodacre, Abdullah Pandor, Catherine Nelson-Piercy, Jahnavi Daru   +8 more
doaj   +1 more source

The effect of active toe movement (AToM) on calf pump function and deep vein thrombosis in patients with acute foot and ankle trauma treated with cast - a prospective randomized study [PDF]

, 2017
Background Patients with foot and ankle trauma treated with cast are advised to perform toe movements to prevent venous thromboembolism (VTE). Our aim was to determine the effect of active toe movement on asymptomatic deep vein thrombosis (DVT) and ...
Alikhan, Raza, Cleves, Andrew, Hickey, Benjamin A., Nokes, Leonard Derek Martin, Perera, Anthony, Pugh, Neil D.   +5 more
core   +1 more source