Results 151 to 160 of about 1,034,549 (408)
THROMBOSIS OF THE MAIN PULMONARY ARTERIES [PDF]
Oscar Magidson, G Jacobson
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Pathogenesis of thrombosis [PDF]
Abstract The hemostatic process is a host defense mechanism to preserve the integrity of the closed high pressure circulatory system. This process must remain inactive but poised to minimize extravasation of blood from the vasculature following tissue injury.
openaire +2 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source
Bone metastasis and steroids are known to activate the coagulation system and induce osteoporosis, pathological bone fractures, and bone pain. Heparanase is a protein known to enhance the hemostatic system and to promote angiogenesis, metastasis, and ...
Keren Asayag+7 more
doaj +1 more source
Coagulation abnormalities and thrombosis in patients with COVID-19
M. Levi, J. Thachil, T. Iba, J. Levy
semanticscholar +1 more source
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao+21 more
wiley +1 more source
Sepsis and obesity: a scoping review of diet-induced obesity murine models
Background Sepsis, the life-threatening host response to infection, is a major cause of mortality. Obesity increases vulnerability to sepsis; however, some degree of obesity may be protective, called the “obesity paradox”.
Mikaela Eng+5 more
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Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu+16 more
wiley +1 more source