Results 31 to 40 of about 78,453 (329)

Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth [PDF]

open access: yes, 1995
Extracellular matrix (ECM) molecules are involved in multiple aspects of cell-to-cell signaling during development and in the adult. In nervous system development, specific recognition processes, e.g., during axonal pathfinding and synaptogenesis involve
Arber, S., P Caroni, S Arber, Caroni, P.
core   +1 more source

Biosensors for Brain Trauma and Dual Laser Doppler Flowmetry: Enoxaparin Simultaneously Reduces Stroke-Induced Dopamine and Blood Flow while Enhancing Serotonin and Blood Flow in Motor Neurons of Brain, In Vivo

open access: yesSensors, 2010
Neuromolecular Imaging (NMI) based on adsorptive electrochemistry, combined with Dual Laser Doppler Flowmetry (LDF) is presented herein to investigate the brain neurochemistry affected by enoxaparin (Lovenox®), an antiplatelet/antithrombotic medication ...
Edwin H. Kolodny, Patricia A. Broderick
doaj   +1 more source

Evaluation of GWAS candidate susceptibility loci for uterine leiomyoma in the multi-ethnic NIEHS uterine fibroid study

open access: yesFrontiers in Genetics, 2015
We evaluated the association of 56 candidate SNPs identified in two published genome-wide association studies (GWAS) of uterine leiomyoma (UL), or fibroids, with the risk and tumor size in the multi-ethnic uterine fibroid study (NIEHS-UFS).
Brahim eAissani   +2 more
doaj   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

open access: yes, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M   +14 more
core   +1 more source

A diverse host thrombospondin-type-1 repeat protein repertoire promotes symbiont colonization during establishment of cnidarian-dinoflagellate symbiosis

open access: yeseLife, 2017
The mutualistic endosymbiosis between cnidarians and dinoflagellates is mediated by complex inter-partner signaling events, where the host cnidarian innate immune system plays a crucial role in recognition and regulation of symbionts.
Emilie-Fleur Neubauer   +6 more
doaj   +1 more source

Structure of human POFUT2 : insights into thrombospondin type 1 repeat fold and O-fucosylation [PDF]

open access: yes, 2012
Protein O-fucosylation is a post-translational modification found on epidermal growth factor-like (EGF) repeats and thrombospondin type 1 repeats (TSR).
Chun-I, Chen
core   +1 more source

O-Glycosylation of thrombospondin type 1 repeats : identification and characterisation of β1,3-glucosyltransferase [PDF]

open access: yes, 2008
Rare types of protein glycosylation often occur in a domain-specific manner required for important biological functions (Okajima et al. 2008). O-linked fucosylation, where the fucose is linked directly to the hydroxyl groups of serine or threonine ...
Keusch, Krisztina
core   +1 more source

Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa

open access: yesEcology and Evolution, 2020
Functional kleptoplasty is a photosymbiotic relationship, in which photosynthetically active chloroplasts serve as an intracellular symbiont for a heterotrophic host.
Jenny Melo Clavijo   +6 more
doaj   +1 more source

Profile of Indian Patients With Membranous Nephropathy

open access: yesKidney International Reports, 2020
Introduction: The majority of primary membranous nephropathy (MN) cases are no longer considered idiopathic with the discovery of the podocytic autoantigens: phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain–containing 7A (THSD7A ...
Priyadarsani Subramanian   +8 more
doaj   +1 more source

Deciphering the complex role of thrombospondin-1 in glioblastoma development

open access: yesNature Communications, 2019
We undertook a systematic study focused on the matricellular protein Thrombospondin-1 (THBS1) to uncover molecular mechanisms underlying the role of THBS1 in glioblastoma (GBM) development.
T. Daubon   +18 more
semanticscholar   +1 more source

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