Results 101 to 110 of about 5,025 (225)

Liver Xenotransplantation: Ethical and Societal Implications

open access: yesXenotransplantation, Volume 33, Issue 2, March/April 2026.
ABSTRACT The shortage of transplantable livers and high waitlist mortality rates have accelerated the clinical translation of liver xenotransplantation. Recent milestones, including extracorporeal perfusion models and gene‐edited pig‐to‐human transplants in both decedents and living patients, indicate that clinical trials may be imminent.
Daniel J. Hurst   +4 more
wiley   +1 more source

Expression of Human Thrombomodulin Prevents Early Thrombocytopenia and Thrombotic Microangiopathy in Pig‐to‐Nonhuman Primate Orthotopic Liver Xenotransplantation

open access: yesXenotransplantation, Volume 33, Issue 2, March/April 2026.
Abstract Background Severe thrombocytopenia and coagulation dysregulation remain major barriers to survival in pig‐to‐primate liver xenotransplantation models. Methods Porcine livers with five genetic modifications (GTKO, CMAHKO, β4GalNT2KO, hCD55, and hTBM) were orthotopically transplanted into four Tibetan macaques under two conventional ...
Zhongqiang Zhang   +17 more
wiley   +1 more source

Secondary thrombotic microangiopathy and eculizumab: A reasonable therapeutic option

open access: yesNefrología (English Edition), 2017
Understanding the role of the complement system in the pathogenesis of atypical haemolytic uraemic syndrome and other thrombotic microangiopathies (TMA) has led to the use of anti-complement therapy with eculizumab in these diseases, in addition to its ...
Elena Román   +8 more
doaj   +1 more source

The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]

open access: yes, 2013
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
core  

Rapid Recognition of Carfilzomib‐Induced Thrombotic Microangiopathy and Early Application of Eculizumab Successfully Rescued Two Relapsed Myeloma Patients

open access: yes
Chronic Diseases and Translational Medicine, Volume 12, Issue 1, Page 63-68, March 2026.
Zi Wang   +6 more
wiley   +1 more source

Toward a New Era: Major Advancements and Future Perspectives in Organ Medicine

open access: yes
Organ Medicine, Volume 3, Issue 1, Page 1-4, March 2026.
Yuanwei Shi, Qiang Zhao, Xiaoshun He
wiley   +1 more source

VEXAS Syndrome and Substance Use Disorders: A Large‐Scale, Propensity‐Matched, Case‐Control Analysis Revealing Immune‐Mediated Comorbidities

open access: yes
International Journal of Dermatology, Volume 65, Issue 3, Page 584-586, March 2026.
Kritin K. Verma   +4 more
wiley   +1 more source

Microangiopathic Anemia without Thrombocytopenia and Kidney Disease in a Child with Diarrhea Caused by Shiga Toxin-Producing Escherichia coli [PDF]

open access: yes, 2017
A child with a history of diarrhea presented with transient anemia, reticolucytosis, and red blood cell fragmentation. Blood pressure and levels of blood platelets, creatinine, and urea were normal, as were results of urinalysis.
Bianchetti, Mario G.   +4 more
core  

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