Results 101 to 110 of about 5,025 (225)
Liver Xenotransplantation: Ethical and Societal Implications
ABSTRACT The shortage of transplantable livers and high waitlist mortality rates have accelerated the clinical translation of liver xenotransplantation. Recent milestones, including extracorporeal perfusion models and gene‐edited pig‐to‐human transplants in both decedents and living patients, indicate that clinical trials may be imminent.
Daniel J. Hurst +4 more
wiley +1 more source
Abstract Background Severe thrombocytopenia and coagulation dysregulation remain major barriers to survival in pig‐to‐primate liver xenotransplantation models. Methods Porcine livers with five genetic modifications (GTKO, CMAHKO, β4GalNT2KO, hCD55, and hTBM) were orthotopically transplanted into four Tibetan macaques under two conventional ...
Zhongqiang Zhang +17 more
wiley +1 more source
Secondary thrombotic microangiopathy and eculizumab: A reasonable therapeutic option
Understanding the role of the complement system in the pathogenesis of atypical haemolytic uraemic syndrome and other thrombotic microangiopathies (TMA) has led to the use of anti-complement therapy with eculizumab in these diseases, in addition to its ...
Elena Román +8 more
doaj +1 more source
The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
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Chronic Diseases and Translational Medicine, Volume 12, Issue 1, Page 63-68, March 2026.
Zi Wang +6 more
wiley +1 more source
Toward a New Era: Major Advancements and Future Perspectives in Organ Medicine
Organ Medicine, Volume 3, Issue 1, Page 1-4, March 2026.
Yuanwei Shi, Qiang Zhao, Xiaoshun He
wiley +1 more source
International Journal of Dermatology, Volume 65, Issue 3, Page 584-586, March 2026.
Kritin K. Verma +4 more
wiley +1 more source
Etiology and outcomes: Thrombotic microangiopathies in pregnancy. [PDF]
Scully M, Neave L.
europepmc +1 more source
Microangiopathic Anemia without Thrombocytopenia and Kidney Disease in a Child with Diarrhea Caused by Shiga Toxin-Producing Escherichia coli [PDF]
A child with a history of diarrhea presented with transient anemia, reticolucytosis, and red blood cell fragmentation. Blood pressure and levels of blood platelets, creatinine, and urea were normal, as were results of urinalysis.
Bianchetti, Mario G. +4 more
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