Results 101 to 110 of about 3,536 (218)

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Immune Thrombocytopenic Purpura Associated With Capnocytophaga Bacteremia

Annals of Internal Medicine: Clinical Cases
Capnocytophaga canimorsus is a gram-negative, capnophilic bacillus commonly found in the oral flora of healthy dogs and cats. C canimorsus can be transmitted to humans via animal bites, scratches, or close contact.
Patricia Zhao, Joseph F. Mort, Maria C. Geba, Gregory R. Madden, Christopher M. Moore   +4 more
doaj   +1 more source

Severe Pediatric Snakebite With Coagulopathy and Compartment Syndrome: Conservative Management With Plasma Exchange

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Therapeutic plasma exchange was successfully used in a child with severe snakebite envenomation complicated by refractory venom‐induced consumptive coagulopathy and suspected compartment syndrome, leading to full recovery and avoidance of surgical intervention.
Zain Mohammed Al Muqbel, Abdulrahman Al‐Majmuei, Ali Haider Ali, Naseem Yusuf Fahad, Reema Ajjawi, Amal Al Dailami, Afshan Lone, Manal Al Maskati, Nasser Mohamed Mansoor   +8 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

The relationship between ADAMTS13 genotype and phenotype in congenital thrombotic thrombocytopenic purpura and characterisation of ADAMTS13 mutants

, 2015
Congenital thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy, usually involving ADAMTS13 gene defects. ADAMTS13 processes the multimeric plasma glycoprotein Von Willebrand factor making it less reactive to platelets.
Underwood, MI
core  

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 389-396, June 2026.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Secondary thrombotic microangiopathy and eculizumab: A reasonable therapeutic option

Nefrología (English Edition), 2017
Understanding the role of the complement system in the pathogenesis of atypical haemolytic uraemic syndrome and other thrombotic microangiopathies (TMA) has led to the use of anti-complement therapy with eculizumab in these diseases, in addition to its ...
Elena Román, Santiago Mendizábal, Isidro Jarque, Javier de la Rubia, Amparo Sempere, Enrique Morales, Manuel Praga, Ana Ávila, José Luis Górriz   +8 more
doaj   +1 more source

A multicenter experience of thrombotic microangiopathies in Turkey: The Turkish Hematology Research and Education Group (ThREG)-TMA01 study

, 2018
Thrombotic microangiopathies (TMAs) are rare, but life-threatening disorders characterized by microangiopathic hemolytic anemia and thrombocytopenia (MAHAT) associated with multiorgan dysfunction as a result of microvascular thrombosis and tissue ...
Sari, Ismail, Guven Cetin, Volkan Karakus, Leylagul Kaynar, Payzin, Bahriye, Sari, Hakan Ismail, Ozgur, Gokhan, Ilhami Kiki, KİKİ, İlhami, Vahap Okan, Emin Kaya, Yılmaz, Mehmet, KUKU, İRFAN, Kiki, I., Karakus, Abdullah, Yılmaz, M., Mehmet Ali Erkurt, KAYNAR, Leylagül, Sarı, İsmail, ERKURT, MEHMET ALİ, Yıldızhan, Esra, Okan, Vahap, Inci Alacacioglu, Ismail Sari, Yildirim, Rahsan, Aydogdu, Ismet, Yildizhan, Esra, Abdullah Karakus, Bahriye Payzin, Akpinar, Seval, Tekgündüz, E., Kaya, A.H., Esra Yildizhan, Cetin, Guven, Fevzi Altuntas, Rahsan Yildirim, Erkurt, M.A., Ozcebe, Osman Ilhami, Mehmet Yılmaz, Demirkan, Fatih, Alacacioglu, I., Altuntas, Fevzi, Kaya, Emin, Ozet, Gulsum, Emre Tekgündüz, Irfan Kuku, Gokhan Ozgur, Kaya, Ali Hakan, Ali Hakan Kaya, Tekgunduz, Emre, Sincan, Gulden, Osman Ilhami Ozcebe, Karakus, Volkan, Ozan Salim, Alacacıoğlu, İnci, Sinem Namdaroglu, Yıldırım, Rahşan, Gulsum Ozet, Seval Akpinar, Yilmaz, Mehmet, Gulden Sincan, Namdaroglu, Sinem, Alacacioglu, Inci, Ozarslan, Ibrahim, Fatih Demirkan, Salim, Ozan, Ismet Aydogdu, Kaynar, L., Ibrahim Ozarslan   +68 more
core   +1 more source