Results 71 to 80 of about 5,025 (225)
The Complement System in Post‐Transplant Kidney Injury
Organ Medicine, EarlyView.
Mengsi Hu
wiley +1 more source
This graphic abstract presents a comprehensive overview of cold agglutinin syndrome (CAS) following haploidentical hematopoietic stem cell transplantation (haplo‐HSCT) based on the content of our letter, including its clinical scenarios, potential triggers, pathophysiological mechanisms, clinical manifestations, as well as therapeutic and management ...
Zhuoyu An +18 more
wiley +1 more source
PROTEOLYTIC PROCESSING OF VON WILLEBRAND FACTOR BY ADAMTS13 AND LEUKOCYTE PROTEASES-rev1-MJHID-2013
ADAMTS13 is a 190 kDa zinc protease encoded by a gene located on chromosome 9q34. This protease specifically hydrolyzes von Willebrand factor (VWF) multimers, thus causing VWF size reduction.
Raimondo De Cristofaro
doaj
ABSTRACT Hereditary tubulointerstitial kidney diseases typically manifest as slowly progressive chronic kidney disease. Rapidly progressive kidney failure with non‐cystic nephromegaly is an exceptionally rare presentation posing significant diagnostic challenges.
Hiroki Ito +11 more
wiley +1 more source
Cancer-related thrombotic microangiopathies: case report and narrative review
Thrombotic manifestations are common in cancer patients and increase morbidity and mortality. They can affect large or small, venous or arterial vessels. Thrombosis of large arteries and veins is much more studied than that of small vessels. Nevertheless,
Micaela La Regina +5 more
doaj +1 more source
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin +14 more
wiley +1 more source
ABSTRACT Purpose Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) effectively treats high‐risk acute lymphoblastic leukemia (ALL), yet challenges persist due to post‐transplant relapse and conditioning regimen toxicities. The determination of an appropriate preconditioning regimen is critical to improving patient outcomes.
Xiaoyan Zhao +6 more
wiley +1 more source
Cardiac involvement in thrombotic microangiopathies
Aim. To describe cardiac involvement in patients with acute thrombotic microangiopathy (TMA). Materials and methods. The case histories of 46 patients with proven TMA, including 17 patients diagnosed with atypical hemolytic uremic syndrome (aHUS) and 29 ...
D S Tuter +6 more
doaj
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice [PDF]
Atypical hemolytic uremic syndrome (aHUS) is frequently associated in humans with loss-of-function mutations in complement-regulating proteins or gain-of-function mutations in complement-activating proteins.
Atkinson, John P +11 more
core +3 more sources

