Results 101 to 110 of about 113,969,313 (213)
, 2003 Prostanoids, i.e. prostaglandins and thromboxane, regulate liver-specific functions both in homeostasis and during defense reactions. For example, prostanoids are released from Kupffer cells, the resident liver macrophages, in response to the ...
Nath, A. +3 more
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, 1987 Since the highly metastatic variant M4 of the mFS6 fibrosarcoma has the peculiar feature of generating larger amounts of immunoreactive thromboxane B2 (TxB2) than the non-metastatic variant (M9), we used the thromboxane synthase inhibitor dazmegrel (UK ...
Niewiarowska, A +5 more
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Resonance Raman Investigation of the Interaction of Thromboxane Synthase with Substrate Analogues
, 2003 Thromboxane synthase is a hemethiolate enzyme that catalyzes the isomerization of prostaglandin H2 to thromboxane A2. We report the first resonance Raman (RR) spectra of recombinant human thromboxane synthase (TXAS) in both the presence and the absence ...
Wang, Lee Ho +2 more
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Effects of thromboxane A2 on lymphocyte proliferation
, 1985 The main cyclooxygenase-dependent arachidonic acid derivatives produced by monocytes and macrophages have been shown to be thromboxane A2 and prostaglandin E2.
Vermylen, Jozef +7 more
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, 1985 The purpose of this investigation was to determine the effects of thromboxane synthase inhibition on vascular responsiveness. To achieve this goal, the effects of thromboxane synthase inhib-itors on mesenteric vascular responses to sympathetic nerve ...
Edwin K. Jackson
core
New developments on thromboxane and prostacyclin modulators - Part I: Thromboxane modulators
, 2004 The pathogenesis of numerous cardiovascular, pulmonary, inflammatory, and thromboembolic diseases can be related to arachidonic acid (AA) metabolites. One of these bioactive metabolites of particular importance is thromboxane A2 (TXA2). It is produced by
Dogne, JM +10 more
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The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]
, 2009 Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
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Glucan synthase of Phytophthora sojae [PDF]
, 2002 Glucans, with the (1-3)-b-glucosidic linkage as major feature, are present in most of the higher plants, in many lower plants, as well as in microorganisms (Stone and Clarke, 1992). The synthesis of (1-3)-b-glucan in vivo is catalysed by the enzyme (1-3)-
Antelo, Luis
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Effect at 6-month on thromboxane A2 pathway.
, 2014 Measures in WT and p53+/− mice fed a regular diet (RD) of A) endothelium-dependent relaxations to acetylcholine (ACh) of aorta segments isolated from WT and p53+/− mice were obtained in presence of thromboxane synthase inhibition (furegrelate, 10 μM), B)
Carol Yu (539483) +5 more
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Associations between thromboxane A synthase 1 gene polymorphisms and the risk of ischemic stroke in a Chinese Han population. [PDF]
Neural Regen Res, 2018 Li L, He ZY, Wang YZ, Liu X, Yuan LY.
europepmc +1 more source