Results 81 to 90 of about 1,598,447 (336)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
High-throughput Technology and High-throughput Factory
Nihon Kessho Gakkaishi, 2003 Structural Genomics has launched over the world including National Project of Protein Structural and Functional Analysis in Japan in a post-genomic era. It remains many bottlenecks to determine the protein structures with SR protein crystallography based on full-genome sequence information in high throughput manner.
Masashi MIYANO +2 more
openaire +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Cooperative Interference Control for Spectrum Sharing in OFDMA Cellular Systems
, 2011 This paper studies cooperative schemes for the inter-cell interference control in orthogonal-frequency-divisionmultiple- access (OFDMA) cellular systems.
Da, Bin, Zhang, Rui
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2011 The achievable throughput of the entire cellular area is investigated, when employing fractional frequency reuse techniques in conjunction with realistically modelled imperfect optical fibre aided distributed antenna systems (DAS) operating in a ...
Ghafoor, Salman +3 more
core
On the Delay-Throughput Tradeoff in Distributed Wireless Networks
, 2009 This paper deals with the delay-throughput analysis of a single-hop wireless network with $n$ transmitter/receiver pairs. All channels are assumed to be block Rayleigh fading with shadowing, described by parameters $(\alpha,\varpi)$, where $\alpha ...
Abouei, Jamshid +2 more
core +2 more sources
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening [PDF]
, 2020 Yuhong Du +7 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nature CommunicationsThe second near-infrared (NIR-II) dyes provide advantages for in vivo imaging, but challenges persist. A primary issue is the lack of practicable strategies to balance emission wavelength and molecular weight, particularly for low-molecular-weight ( 1000
Miantai Ye +6 more
doaj +1 more source