Results 51 to 60 of about 330 (140)
© 2022 Elsevier B.V.Polygonum multiflorum Thunb. (PM) has been used since ancient times as Chinese traditional medicine. 2,3,5,4′-tetrahydroxystilbene-2-O-β-glucoside (THSG), a major active component in its extracts, has been reported to exhibit numerous
Zhang, Jing +9 more
core +1 more source
Abstract After Ghana gained independence in 1957, only two Collective Management Organizations (CMOs) have ever been established to collect and distribute royalties for copyright owners in musical works—the Copyright Society of Ghana (COSGA), established in 1986, and the Ghana Music Rights Organization (GHAMRO) established in 2011, which presently ...
Kow Abekah‐Wonkyi
wiley +1 more source
THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B–CaMKII–ERK1/2 pathway
The potential therapeutic targeting of PINK1-PARK2-mediated mitophagy against cerebral ischemia/reperfusion (CI/R) injury involves the pathophysiological processes of neurovascular unit (NVU) and is closely associated with N-methyl-D-aspartate receptors (NMDARs) commonly expressed in NVU.
Tonghe Liu +11 more
openaire +2 more sources
Genetic mutations disrupt the coordinated mode of tyrosinase's intra‐melanosomal domain
Abstract Oculocutaneous albinism type 1 is a genetic disorder caused by the disruption of tyrosinase activity in the melanogenesis pathway. The tyrosinase's intramelanosomal domain can be subdivided into the catalytic and Cys‐rich subdomains, integral for protein stability and catalytic activity.
Sarah Toay, Yuri V. Sergeev
wiley +1 more source
THSG prevents the loss of nNOS expression in diabetic ilea.
(A) Representative photographs of sections of ilea from normal control, diabetic and THSG-treated diabetic mice stained for nNOS as well as negative control. Arrows indicate nNOS-positive area (stained brown). (B) nNOS immunostaining density was measured
Yong-Li Yan (296124) +5 more
core +1 more source
This study demonstrates that resveratrol inhibits the activation of the Wnt/β‐catenin signaling pathway by downregulating PRDX4 expression, thereby suppressing renal cell carcinoma (RCC) progression. In vitro and in vivo experiments confirmed that resveratrol reduces RCC cell viability, migration, invasion, and tumor growth while promoting apoptosis ...
Hongzhi Li +4 more
wiley +1 more source
Influence Factors on the Hepatotoxicity of Polygoni Multiflori Radix
Background. Chinese herbal medicine (CHM) with reported hepatotoxicity is identified, in which Polygoni Multiflori Radix (HSW) attracts most attention. According to the Traditional Chinese Medicine (TCM) theory, processing is believed to be able to reduce the toxicity of HSW, but in publications, both processed and unprocessed HSW are reported to cause
Yun Wei +4 more
wiley +1 more source
Oxidative stress is an important pathological mechanism in various liver diseases. Polygonum multiflorum Thunb. (PM) can be used for the treatment of diseases associated with aging, hyperlipidemia, and oxidative stress in traditional Chinese medicine.
En-Yuan Lin +6 more
wiley +1 more source
ABSTRACT Chronic liver diseases frequently progress to liver fibrosis, characterized by the accumulation of extracellular matrix (ECM) proteins and the formation of fibrous scars. This fibrous tissue disrupts normal liver architecture, impairing its physiological functions.
Sathish Kumar Mungamuri +2 more
wiley +1 more source
Generation of Multiple‐Depth 3D Computer‐Generated Holograms from 2D‐Image‐Datasets Trained CNN
This study presents a novel method for generating computer‐generated holograms (CGHs) of 3D scenes using a CNN trained on 2D image datasets. By creating virtual depth (VD) images with a uniform statistical distribution, this approach enables fast reconstructions, achieving phase‐only holograms with an average PSNR of 34.7 dB and SSIM of 0.836 ...
Xingpeng Yan +10 more
wiley +1 more source

