Results 1 to 10 of about 16,615 (159)

Study on the differential hepatotoxicity of raw polygonum multiflorum and polygonum multiflorum praeparata and its mechanism

BMC Complementary Medicine and Therapies, 2022
Background Polygonum multiflorum (PM), a widely used traditional Chinese medicine herb, is divided into two forms, namely raw polygonum multiflorum (RPM) and polygonum multiflorum praeparata (PMP), according to the processing procedure. Emerging data has
Chaowen Huang, Yu Jiang, Qing Bao, Lu Wang, Lin Tang, Yanjuan Liu, Lei Yang   +6 more
doaj   +4 more sources

Therapeutic Effect of Polygonum multiflorum Extract on Gouty Arthritis in Rats [PDF]

BIO Web of Conferences
Objective: The investigation of the efficacy of Polygonum multiflorum extract on gouty arthritis in rats. Method: Thirty male SD rats were randomly divided into blank control group, gouty arthritis model group, colchicine group, low, medium, and high ...
Tan Jinyi, Liu Qihang, He Lian
doaj   +2 more sources

Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA

Foods, 2022
A rapid and effective ultra-high performance liquid chromatography (UHPLC) method was developed for the determination of five anthraquinones (emodin, physcion, aloe-emodin, rhein, and chrysophanol) in Polygonum multiflorum.
Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo   +7 more
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Analyze the Effect of Steaming on the Chemical Constituents, Defecation and Liver Injury of Polygonum Multiflorum Radix (Heshouwu) by Multiple Analysis Techniques Combined with Multivariate Statistics

Molecules, 2022
Steaming is a characteristic pharmaceutical skill in Traditional Chinese Medicine (TCM). Polygonum multiflorum radix (PM) and its steamed products have been used in Asia for centuries.
Xiaolei Du, Lili Xu, Zhe Zhang, Yang Wang, Huifen Li, Weiliang Cui, Huibin Lin   +6 more
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Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease

Frontiers in Pharmacology
BackgroundAlzheimer’s disease (AD) is a progressive neurodegenerative disorder with no effective treatment currently available. The Panax ginseng C.A.Mey. and Polygonum multiflorum Thunb.
Shuang-Cheng Ma
exaly   +3 more sources

A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT)

PLoS ONE, 2022
Background and aims We hypothesized that a drug’s clinical signature (or phenotype) of liver injury can be assessed and used to quantitatively develop a computer-assisted DILI causality assessment-tool (DILI-CAT).
Hans L. Tillmann, Ayako Suzuki, Michael Merz, Richard Hermann, Don C. Rockey   +4 more
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Molecular mechanism of polygonum multiflorum in the treatment of androgenic alopecia: based on bioinformatics and molecular docking method

Pifu-xingbing zhenliaoxue zazhi, 2022
Objective To explore molecular mechanisms of polygonum multiflorum in the treatment of androgenic alopecia and to provide underlying drug targets. Methods Bioinformatics analysis tool for molecular mechanism of Traditional Chinese Medicine and five ...
Dongyu CHEN, Xiaoyu YANG, Hongxin WANG, Wenlong FAN, Yuqing HE   +4 more
doaj   +1 more source

A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside

Frontiers in Pharmacology, 2022
Polygonum multiflorum Thunb. (He-shou-wu in Chinese), a Chinese botanical drug with a long history, is widely used to treat a variety of chronic diseases in clinic, and has been given the reputation of “rejuvenating and prolonging life” in many places. 2,
Cheng Wang, Shu Dai, Lihong Gong, Ke Fu, Cheng Ma, Yanfang Liu, Honglin Zhou, Yunxia Li   +7 more
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Composite double-layer microneedle loaded with traditional Chinese medicine for the treatment of androgenic alopecia

Medicine in Novel Technology and Devices, 2023
Androgenetic alopecia (AGA) is an androgen-mediated alopecia affected by both genes and hormones. Medication is a relatively common treatment. As a new drug delivery method, microneedles (MNs) can effectively break through the stratum corneum barrier ...
Ruoxi Wang, Jiangge Wang, Haiqiang Gao, Xiangyi Liao, Chunyang Ma, Xufeng Niu   +5 more
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Emodin in cardiovascular disease: The role and therapeutic potential

Frontiers in Pharmacology, 2022
Emodin is a natural anthraquinone derivative extracted from Chinese herbs, such as Rheum palmatum L, Polygonum cuspidatum, and Polygonum multiflorum. It is now also a commonly used clinical drug and is listed in the Chinese Pharmacopoeia.
Yuanyuan Guo, Yuanyuan Guo, Rongzhen Zhang, Wenlan Li   +3 more
doaj   +1 more source