Results 21 to 30 of about 16,615 (159)

Diagnosis and Management of Drug-Induced Liver Injury After the Use of Polygonum multiflorum [PDF]

open access: yes, 2022
Polygonum multiflorum, a species of flowering plant in the buckwheat family, is widely used in alternative medicine. However, a growing body of literature has implicated P. multiflorum as a cause of drug-induced liver injury.
Gill, Ryan M.   +4 more
core   +1 more source

Effects of Different Processed Products of Polygonum multiflorum on the Liver [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2020
Objective. Based on in vitro and in vivo experimental studies, the changes of the main components of Polygonum multiflorum and different processed products and their effects on hepatotoxicity were investigated. Methods. The components of different processed products of Polygonum multiflorum were determined by HPLC.
Ruo-Lan Li   +7 more
openaire   +2 more sources

Effects of Polygonum multiflorum extract on DNA methylation and gene transcription in brain tissue of aging mice

open access: yesDi-san junyi daxue xuebao, 2020
Objective To determine the effect of Polygonum multiflorum extract (PME) on DNA methylation and transcriptome levels in the brain tissue of D-galactose-induced senescence C57BL/6 mice, and explore its mechanism of delaying aging.
ZOU Jiayi   +4 more
doaj   +1 more source

Reduction of Atherosclerosis in Cholesterol-Fed Rabbits and Decrease of Expressions of Intracellular Adhesion Molecule-1 and Vascular Endothelial Growth Factor in Foam Cells by a Water-Soluble Fraction of Polygonum multiflorum

open access: yesJournal of Pharmacological Sciences, 2005
Polygonum multiflorum stilbeneglycoside (PMS) is a water-soluble fraction of Polygonum multiflorum Thunb., one of the most famous tonic traditional Chinese medicines, that has protective effects on the cardiovascular system.
Peng-Yuan Yang   +8 more
doaj   +1 more source

Comprehensive characterization of natural products of Polygonum multiflorum by cheminformatics analysis

open access: yesPharmacological Research - Modern Chinese Medicine, 2023
Introduction: A growing body of evidence has suggested that Polygonum multiflorum Thunb. (PM) may cause PM-herb-induced liver injury (PM-HILI). However, the compounds triggering PM-HILI remain controversial.
Xiaowen Hu   +5 more
doaj   +1 more source

Effect of silver nitrate and putrescine on in vitro shoot organogenesis of Polygonum multiflorum [PDF]

open access: yes, 2022
Polygonum multiflorum is a flowering plant that belongs to the family Polygonaceae and it is commonly used for medicinal and ornamental purposes. Few studies have been studied about the regeneration of this species.
Kim, Haeng-Hoon   +4 more
core   +1 more source

Chemoenzymatic Synthesis of Two New Halogenated Coumarin Glycosides as Potential Antifungal Agents

open access: yesNatural Product Communications, 2012
Two new potential antifungal coumarin glycosides, 6-chlorocoumarin 7- O - β -D-glucopyranoside ( 1 ) and 7-hydroxy-4-trifluoromethyl-coumarin 5- O - β -D-glucopyranoside ( 2 ), were synthesized via enzyme-mediated glycosylation of the respective aglycone,
Liangbin Zhou   +4 more
doaj   +1 more source

Herb-Induced Liver Injury Related to Reynoutria multiflora (Thunb.) Moldenke: Risk Factors, Molecular and Mechanistic Specifics

open access: yesFrontiers in Pharmacology, 2021
Herbal medicine is widely used in Asia as well as the west. Hepatotoxicity is one of the most severe side effects of herbal medicine which is an increasing concern around the world.
Xing-Ran Zhai   +7 more
doaj   +1 more source

Investigation of the idiosyncratic hepatotoxicity of Polygonum multiflorum Thunb. through metabolomics using GC-MS

open access: yesBMC Complementary Medicine and Therapies, 2021
Background The idiosyncratic hepatotoxicity of Polygonum multiflorum (PM) has attracted considerable interest, but the idiosyncratically hepatotoxic components and endogenous metabolite changes resulting from idiosyncratic hepatotoxicity of PM are not ...
Yan Lin   +7 more
doaj   +1 more source

New phenolic constituents obtained from Polygonum multiflorum

open access: yesChinese Herbal Medicines, 2020
To isolate the phenolic compounds obtained from the dried roots of Polygonum multiflorum and investigate their pharmacological activities.The chemical constituents were isolated and purified by combining them with a macroporous resin (DM-8), MCI gel, and Sephadex LH-20 and by performing ODS column chromatography.
Yang, Jian-bo   +8 more
openaire   +2 more sources

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