Results 61 to 70 of about 9,507 (296)
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
A spectroscopic investigation of novel doped glasses for active infrared devices
, 2006 A number of novel doped glasses have been studied for their potential as infrared amplifier materials. Optical amplifiers which operate outside of the C-band are likely to form part of future optical telecoms systems.
Aronson, Jonathan Edward
core +1 more source
Magnetic excitations in thulium
, 1988 We have observed, for the first time, magnetic excitations in a single crystal of thulium, using inelastic neutron spectroscopy. In the ferromagnetic phase three modes with energies around 4 meV, 8 meV and 15 meV were clearly seen. We have considered our
McEwen K A +3 more
core +1 more source
1.8-μm thulium microlasers integrated on silicon [PDF]
, 2018 A key challenge for silicon photonic systems is the development of compact on-chip light sources. Thulium-doped fiber and waveguide lasers have recently generated interest for their highly efficient emission around 1.8 μm, a wavelength range also of ...
Watts, Michael +9 more
core +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The Journal of Engineering, 2014 Simple, low-cost and stable passive Q-switched thulium-doped fibre lasers (TDFLs) operating at 1892.4 and 1910.8 nm are demonstrated using 802 and 1552 nm pumping schemes, respectively, in conjunction with a multi-walled carbon nanotubes (MWCNTs ...
Norazlina Saidin +8 more
doaj +1 more source
Development of thulium-doped fibre amplifiers for the 2μm waveband [PDF]
, 2018 In this paper we show the analysis of Thulium Doped Fibre Amplifier(TDFA) gain dependence on pump laser wavelength and thulium doped fibre length. Thulium doped fibres of lengths varying from 0.5m to 3m are pumped with 785nm and 1550nm lasers in single ...
Kavanagh, Niamh +7 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source