Results 111 to 120 of about 184,554 (216)

TSLP‐targeting therapy: Beyond allergy?

Clinical and Translational Medicine, 2023
Risa Ebina‐Shibuya, Warren J. Leonard
doaj   +1 more source

Increased serum thymic stromal lymphopoietin in children with atopic dermatitis

, 2010
The present study investigated the relationship between serum thymic stromal lymphopoietin (TSLP) levels and the presence and severity of atopic dermatitis (AD).
김경원, 손명현, 홍정연, 지혜미, 이은별, 김규언, Kyu-Earn Kim, Kyung Won Kim, Hye Mi Jee, Myung Hyun Sohn, Eun Byoul Lee, Jung Yeon Hong   +11 more
core   +1 more source

Extracellular Vesicles in Dermatology: Where Are We and What Lies Ahead?

Experimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as key players in skin biology, mediating intercellular communication across diverse physiological and pathological contexts. In this review, we critically assess the current understanding of EVs in dermatology, highlighting their roles in skin homeostasis, ageing, inflammation, wound healing and ...
Ines Martic, Alessandro Paolini, Stefania Paola Bruno, Andrea Gallego, Dorottya Ádám, Sedat Odabas, Şebnem Erçelen Ceylan, Emanuela Camera, Paloma Pérez, Attila Oláh, Andrea Masotti, Mirjana Nacka‐Aleksić, Danuta Gutowska‐Owsiak, Nsrein Ali, Maria Cavinato   +14 more
wiley   +1 more source

Thymic Stromal Lymphopoietin (TSLP)

Current allergy and asthma reports
Purpose of the Review: Thymic stromal lymphopoietin (TSLP) is increasingly recognized for its pivotal role in the pathogenesis of various epithelial-driven chronic inflammatory diseases. This review navigates the existing evidence on TSLP, with a particular focus on asthma, before delving into the current understanding of its role in chronic ...
de Corso, Eugenio, Hellings, Peter W., Fokkens, Wytske J., Klimek, Ludger, Peters, Anju T., Scadding, Glenis K., Desrosiers, Martin, Lee, Stella E., Mullol, Joaquim   +8 more
openaire   +1 more source

Potential of alarmin-targeted bispecific and combination therapies in airway disease

Frontiers in Allergy
Thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 are epithelial-derived proinflammatory alarmin cytokines that drive inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD).
H. Kiyomi Komori, Hector Ortega
doaj   +1 more source

A Comparison for Type 2 Cytokines and Lesional Inflammatory Infiltrations in Bullous Pemphigoid and Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology, 2022
Yu-qing Hu, Jian-zhong Zhang Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic ChinaCorrespondence: Jian-zhong Zhang, Tel +86-10-88325472, Fax +86-10-68318386, Email rmzjz@126.comBackground: Bullous pemphigoid (BP)
Hu YQ, Zhang JZ
doaj  

IL-33 and Thymic Stromal Lymphopoietin in mast cell functions

, 2016
Thymic Stromal Lymphopoietin (TSLP) and Interleukin 33 (IL-33) are two cytokines released by cells that are in proximity to our environment, e.g., keratinocytes of the skin and epithelial cells of the airways.
Maria Elizabeth Ketelaar, Gunnar Nilsson, Anna Zoltowska, Ketelaar, Maria Elizabeth, Saluja, Rohit, Zoltowska, Anna, Nilsson, Gunnar, Rohit Saluja, Ketelaar, ME, Nilsson, G,, Zoltowska, A, Saluja, R   +11 more
core   +1 more source

The last step to achieve barrier damage control

Frontiers in Immunology
Heterogeneity characterises inflammatory diseases and different phenotypes and endotypes have been identified. Both innate and adaptive immunity contribute to the immunopathological mechanism of these diseases and barrier damage plays a prominent role ...
Ilaria Baglivo, Stefania Colantuono, Arianna Lumaca, Alfredo Papa, Antonio Gasbarrini, Cristiano Caruso   +5 more
doaj   +1 more source

Mechanistic study on the alleviation of LPS-induced hepatocyte injury by thymic stromal lymphopoietin

Guangxi Yike Daxue xuebao
Objective To explore the mechanism of thymic stromal lymphopoietin (TSLP) in regulating lipopolysaccharide (LPS) -induced inflammation in mouse hepatocytes. Methods Ten male C57BL/6J wild-type (WT) mice and 10 male TSLP receptor-deficient (TSLPR-/-) mice
Jiarui ZHANG, Shaolei WU, Shilai LI
doaj   +1 more source

Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor

, 2000
The cellular receptor for murine thymic stromal lymphopoietin (TSLP) was detected in a variety of murine, but not human myelomonocytic cell lines by radioligand binding.
Di Santo, James P., Ziegler, Steven F., John E. Sims, Paxton, Raymond, Andrew G. Farr, Linda S. Park, Werner Muller, Nancy A. Jenkins, Largaespada, David A., Steven F. Ziegler, Garka, Kirsten, Sims, John E., Farr, Andrew G., Park, Linda S., Unja Martin, Brian Gliniak, Neal G. Copeland, Kirsten Garka, Martin, Unja, Copeland, Neal G., James P. Di Santo, Muller, Werner; id_orcid, Gliniak, Brian, Jenkins, Nancy A., David A. Largaespada, Morrissey, Philip J., Philip J. Morrissey, Raymond Paxton   +27 more
core   +1 more source