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Preparation of recombinant human thymic stromal lymphopoietin protein

Preparative Biochemistry & Biotechnology, 2017
Human thymic stromal lymphopoietin (hTSLP) protein plays a central role in inflammation. Characterizing properties of hTSLP requires a recombinant overexpression system that produces correctly folded, active hTSLP. In this report, an efficient overexpression system for the production of hTSLP was developed.
Yanlu Zhang   +6 more
openaire   +2 more sources

The role of thymic stromal lymphopoietin in cutaneous disorders

Archives of Dermatological Research
Thymic Stromal Lymphopoietin (TSLP) is an important cytokine that invokes early immune responses. TSLP, an IL-7-like cytokine encoded by the TSLP gene, activates JAK1 and JAK2 signaling pathways, stimulating dendritic cells to induce inflammatory Th2 cells.
Alexander J. Jafari   +2 more
openaire   +2 more sources

Thymic stromal lymphopoietin: a central regulator of allergic asthma

Expert Opinion on Therapeutic Targets, 2014
Epithelial cell-derived mediators have emerged as key players for instigating local remodeling and the associated cellular inflammation in asthmatic airways. In particular, the epithelial-derived cytokine, thymic stromal lymphopoietin (TSLP), has been identified as a master switch for allergic inflammation.TSLP is expressed by structural and immune ...
Brittany, Watson, Gail M, Gauvreau
openaire   +2 more sources

Molecular cloning and characterization of equine thymic stromal lymphopoietin

Veterinary Immunology and Immunopathology, 2010
Thymic stromal lymphopoietin (TSLP) is a novel cytokine that plays a central role in T helper 2 (Th2) cell differentiation and allergic inflammation. It is predominantly expressed by epithelial cells, and its expression is increased in patients with atopic dermatitis and asthma.
Klukowska-Rötzler J   +4 more
openaire   +4 more sources

Functions of thymic stromal lymphopoietin in non-allergic diseases

Cellular Immunology, 2015
Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine produced mainly by epithelial cells. Many studies indicate that TSLP contributes to promote T helper (Th) 2 immune responses which are associated with the pathogenesis of allergic inflammatory diseases.
Guoqing, Ying   +3 more
openaire   +2 more sources

Thymic Stromal Lymphopoietin (TSLP)

Science-Business eXchange, 2013
Steven F. Ziegler   +5 more
openaire   +2 more sources

Thymic Stromal Lymphopoietin (TSLP)

2003
Steven D. Levin   +3 more
openaire   +1 more source

Thymic Stromal Lymphopoietin (TSLP)

2017
Jianguang Du, Baohua Zhou
openaire   +1 more source

Effects of Resveratrol on Thymic Stromal Lymphopoietin Expression in Mast Cells

Medicina (Lithuania), 2021
Hyun-Ja Jeong   +2 more
exaly  

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