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Preparation of recombinant human thymic stromal lymphopoietin protein
Preparative Biochemistry & Biotechnology, 2017Human thymic stromal lymphopoietin (hTSLP) protein plays a central role in inflammation. Characterizing properties of hTSLP requires a recombinant overexpression system that produces correctly folded, active hTSLP. In this report, an efficient overexpression system for the production of hTSLP was developed.
Yanlu Zhang +6 more
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The role of thymic stromal lymphopoietin in cutaneous disorders
Archives of Dermatological ResearchThymic Stromal Lymphopoietin (TSLP) is an important cytokine that invokes early immune responses. TSLP, an IL-7-like cytokine encoded by the TSLP gene, activates JAK1 and JAK2 signaling pathways, stimulating dendritic cells to induce inflammatory Th2 cells.
Alexander J. Jafari +2 more
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Thymic stromal lymphopoietin: a central regulator of allergic asthma
Expert Opinion on Therapeutic Targets, 2014Epithelial cell-derived mediators have emerged as key players for instigating local remodeling and the associated cellular inflammation in asthmatic airways. In particular, the epithelial-derived cytokine, thymic stromal lymphopoietin (TSLP), has been identified as a master switch for allergic inflammation.TSLP is expressed by structural and immune ...
Brittany, Watson, Gail M, Gauvreau
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Molecular cloning and characterization of equine thymic stromal lymphopoietin
Veterinary Immunology and Immunopathology, 2010Thymic stromal lymphopoietin (TSLP) is a novel cytokine that plays a central role in T helper 2 (Th2) cell differentiation and allergic inflammation. It is predominantly expressed by epithelial cells, and its expression is increased in patients with atopic dermatitis and asthma.
Klukowska-Rötzler J +4 more
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Functions of thymic stromal lymphopoietin in non-allergic diseases
Cellular Immunology, 2015Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine produced mainly by epithelial cells. Many studies indicate that TSLP contributes to promote T helper (Th) 2 immune responses which are associated with the pathogenesis of allergic inflammatory diseases.
Guoqing, Ying +3 more
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Thymic Stromal Lymphopoietin (TSLP)
Science-Business eXchange, 2013Steven F. Ziegler +5 more
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Effects of Resveratrol on Thymic Stromal Lymphopoietin Expression in Mast Cells
Medicina (Lithuania), 2021Hyun-Ja Jeong +2 more
exaly
Exploring the biological mechanisms of thymic stromal lymphopoietin
British Journal of Dermatology, 2015openaire +2 more sources

