Results 221 to 230 of about 21,196 (261)
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Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin
Nature Immunology, 2019Liang Ye, Daniel Schnepf, Jan Becker
exaly +2 more sources
Thymic stromal lymphopoietin [PDF]
Annals of the New York Academy of Sciences, 2010 Thymic stromal lymphopoietin (TSLP) is an epithelial cell‐derived cytokine expressed in skin, gut, lungs, and thymus. TSLP signals via a TSLP receptor (TSLPR), a heterodimer of the IL‐7 receptor α chain and the TSLPR chain. The TSLPR chain is closely related to the common receptor γ chain that is expressed on a wide range of cell types in the adaptive ...
Rui He
exaly +3 more sources
Science Translational Medicine, 2022
Recruitment of regulatory T cells (Tregs) to tumors is a hallmark of cancer progression. Tumor-derived factors, such as the cytokine thymic stromal lymphopoietin (TSLP), can influence Treg function in tumors. In our study, we identified a subset of Tregs
K. Obata-Ninomiya +3 more
semanticscholar +1 more source
Recruitment of regulatory T cells (Tregs) to tumors is a hallmark of cancer progression. Tumor-derived factors, such as the cytokine thymic stromal lymphopoietin (TSLP), can influence Treg function in tumors. In our study, we identified a subset of Tregs
K. Obata-Ninomiya +3 more
semanticscholar +1 more source
Journal of Toxicology and Environmental Health, Part A, 2021
Atopic dermatitis is a chronic inflammatory skin disease, of which incidence is closely related to exposure to environmental pollutants and allergens. Thymic stromal lymphopoietin (TSLP) plays an important role in the early stages of atopic dermatitis ...
Jae Kwon Lee +9 more
semanticscholar +1 more source
Atopic dermatitis is a chronic inflammatory skin disease, of which incidence is closely related to exposure to environmental pollutants and allergens. Thymic stromal lymphopoietin (TSLP) plays an important role in the early stages of atopic dermatitis ...
Jae Kwon Lee +9 more
semanticscholar +1 more source
Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis [PDF]
Nature Medicine, 2013 Eosinophilic esophagitis (EoE) is a food allergy-associated inflammatory disease characterized by esophageal eosinophilia. Current management strategies for EoE are nonspecific, and thus there is a need to identify specific immunological pathways that could be targeted to treat this disease. EoE is associated with polymorphisms in the gene that encodes
Mario Noti +2 more
exaly +4 more sources
Analytical Chemistry
In this letter, a sensitive microfluidic immunosensor chip was developed using tetrakis(4-aminophenyl)ethene (TPE)-derived covalent organic frameworks (T-COF) as aggregation-induced electrochemiluminescence (AIECL) emitters and nanobodies as efficient ...
Yue Jia +9 more
semanticscholar +1 more source
In this letter, a sensitive microfluidic immunosensor chip was developed using tetrakis(4-aminophenyl)ethene (TPE)-derived covalent organic frameworks (T-COF) as aggregation-induced electrochemiluminescence (AIECL) emitters and nanobodies as efficient ...
Yue Jia +9 more
semanticscholar +1 more source
Preparation of recombinant human thymic stromal lymphopoietin protein
Preparative Biochemistry & Biotechnology, 2017Human thymic stromal lymphopoietin (hTSLP) protein plays a central role in inflammation. Characterizing properties of hTSLP requires a recombinant overexpression system that produces correctly folded, active hTSLP. In this report, an efficient overexpression system for the production of hTSLP was developed.
Yanlu Zhang +6 more
openaire +2 more sources
Thymic stromal lymphopoietin and atopic diseases
Revue Française d'Allergologie, 2014Abstract Studies from the last ten years have seen great progress in recognizing the role of cytokine thymic stromal lymphopoietin (TSLP) in pathogenesis of atopic diseases, particularly atopic dermatitis (AD) and asthma. We provide here a review of the findings from four aspects: (1) TSLP: expression triggers and cellular sources; (2) TSLP receptor:
J.M. Leyva-Castillo, M. Li
openaire +1 more source
Clinical and Experimental Allergy, 2020
Genome‐wide association studies have identified associations of the single nucleotide polymorphism rs1837253 in the thymic stromal lymphopoietin (TSLP) gene with asthma, allergic disease and eosinophilia.
Amy Moorehead +8 more
semanticscholar +1 more source
Genome‐wide association studies have identified associations of the single nucleotide polymorphism rs1837253 in the thymic stromal lymphopoietin (TSLP) gene with asthma, allergic disease and eosinophilia.
Amy Moorehead +8 more
semanticscholar +1 more source