Results 121 to 130 of about 12,710 (220)

Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway

Biomolecules
Disruption of the airway epithelium triggers a defensive immune response that begins with the production and release of alarmin cytokines. These epithelial-derived alarmin cytokines, including thymic stromal lymphopoietin (TSLP), are produced in response
Danica L. Brister, Hafsa Omer, Christiane E. Whetstone, Maral Ranjbar, Gail M. Gauvreau   +4 more
doaj   +1 more source

Serum thymic stromal lymphopoietin (TSLP) levels in atopic dermatitis patients: a systematic review and meta-analysis. [PDF]

Clin Exp Med, 2023
García-Reyes MM, Zumaya-Pérez LC, Pastelin-Palacios R, Moreno-Eutimio MA.   +3 more
europepmc   +1 more source

Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy.

International journal of clinical and experimental pathology, 2008
The rising worldwide prevalence of asthma has intensified interest in the natural history of asthma. An improved understanding of the genetic, environmental, and developmental factors contributing to the inception and exacerbation of asthma will be crucial to efforts to devise effective preventive and therapeutic interventions.
Esnault, S. (Stéphane), Rosenthal, L.A. (Louis A), Wang, D-S. (Deng-Shun), Malter, J.S. (James S)   +3 more
openaire   +4 more sources

Successful Treatment of Eosinophilic Chronic Rhinosinusitis and Secretory Otitis Media in Refractory Asthma With Thymic Stromal Lymphopoietin (TSLP) Receptor Monoclonal Antibody. [PDF]

Cureus, 2023
Kawashima K, Matsuno O, Okuno M, Kawabe T, Hanada Y.   +4 more
europepmc   +1 more source

Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]

, 2018
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan, Alivernini, Alivernini, Alvaro-Gracia, Anderson, Asquith, Bamboat, Behrens, Bell, Ben Nasr, Benham, Black, Bluml, Brentano, Burmester, Burmester, Burmester, Catrina, Cauli, Cheung, Chu, Chu, Couzin-Frankel, Cramer, Cross, den Berg, den Brand, Dillon, Donlin, Ehrenstein, Elmesmari, Ferraccioli, Field, Firestein, Frank-Bertoncelj, Gao, Ginhoux, Greven, Guiducci, Guo, Hambleton, Hamilton, Haschka, Herenius, Hogg, Hurst, Iliev, James, Jongbloed, Kaplanski, Kokkonen, Kollias, Konig, Kriegler, Kurowska-Stolarska, Kurowska-Stolarska, Kurowska-Stolarska, Lemke, Malmstrom, Mann, McInnes, McInnes, McInnes, McLoughlin, Midwood, Miller, Misharin, Misso, Moret, Moret, Morton, Murata, Na, Nagy, Nassar, Ng, O'Connell, O'Connell, O'Keeffe, Ohshima, Okada, Paolino, Park, Rajasekhar, Ramwadhdoebe, Rauber, Reynolds, Roberts, Rothlin, Rupaimoole, Rycke, Sacre, Schett, Singh, Smith, Smith, Smolen, Sokolove, Stanczyk, Steidl, Takeuchi, Tannahill, Thai, Tsoumakidou, Udalova, Vandenabeele, Villani, Watts, Weinblatt, Weiss, Williamson, Wolf, Xiong, Yeo, Yu, Zou   +115 more
core   +1 more source

Role of thymic stromal lymphopoietin (TSLP) in asthma

, 2021
Thymic Stromal Lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a murine thymic stromal cell line and characterized as a lymphocyte growth factor. TSLP is predominantly expressed by lung and gut epithelial cells, keratinocytes, and by dendritic cells (DCs). TSLP can be produced also by airway smooth muscle (ASM) cells, mast cells,
openaire   +1 more source

A dual computational and experimental strategy to enhance TSLP antibody affinity for improved asthma treatment.

PLoS Computational Biology
Thymic stromal lymphopoietin is a key cytokine involved in the pathogenesis of asthma and other allergic diseases. Targeting TSLP and its signaling pathways is increasingly recognized as an effective strategy for asthma treatment.
Yitong Lv, He Gong, Xuechao Liu, Jia Hao, Lei Xu, Zhiwei Sun, Changyuan Yu, Lida Xu   +7 more
doaj   +1 more source

Inflammatory Cytokine TSLP Stimulates Platelet Secretion and Potentiates Platelet Aggregation via a TSLPR-Dependent PI3K/Akt Signaling Pathway

Cellular Physiology and Biochemistry, 2015
Aims: Thymic stromal lymphopoietin (TSLP) plays an important role in inflammatory diseases and is over-expressed in human atherosclerotic artery specimens.
Jangchuan Dong, Jing Lin, Boyuan Wang, Shaolin He, Chun Wu, Kishan Kumar Kushwaha, Nilesh Mohabeer, Yousu Su, Hongcheng Fang, Kai Huang, Dazhu Li   +10 more
doaj   +1 more source

A Distinct Sensitization Pattern Associated with Asthma and the Thymic Stromal Lymphopoietin (TSLP) Genotype

Allergology International, 2013
Atopy is a phenotypically heterogeneous condition, and the extent to which atopy accounts for asthma is controversial. In this study, we aimed to identify the presence of distinct sensitization patterns to common inhaled allergens and their association with asthma, allergic rhinitis and TSLP genotypes.We studied 1683 adults from Tsukuba, a city in ...
Hiroaki Iijima, Yoshiko Kaneko, Hideyasu Yamada, Yohei Yatagai, Hironori Masuko, Tohru Sakamoto, Takashi Naito, Tomomitsu Hirota, Mayumi Tamari, Satoshi Konno, Masaharu Nishimura, Emiko Noguchi, Nobuyuki Hizawa   +12 more
openaire   +3 more sources

木村病においてはTSLP, TSLP受容体の発現が亢進している [PDF]

, 2015
博士（医学） 乙第2870号（主論文の要旨、要約、審査結果の要旨）博士（医学 ...
崎谷 恵理
core   +1 more source