Results 111 to 120 of about 139,364 (204)

Respiratory syncytial virus induces functional thymic stromal lymphopoietin receptor in airway epithelial cells

, 2013
Michael M Miazgowicz,1,2 Molly S Elliott,3 Jason S Debley,3 Steven F Ziegler1,21Immunology Program, Benaroya Research Institute, Seattle, WA, 2Department of Immunology, University of Washington School of Medicine, Seattle, WA, 3The Center for Immunology ...
Ziegler SF, Elliott MS, Debley JS, Miazgowicz MM   +3 more
core  

Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy.

International journal of clinical and experimental pathology, 2008
The rising worldwide prevalence of asthma has intensified interest in the natural history of asthma. An improved understanding of the genetic, environmental, and developmental factors contributing to the inception and exacerbation of asthma will be crucial to efforts to devise effective preventive and therapeutic interventions.
Esnault, S. (Stéphane), Rosenthal, L.A. (Louis A), Wang, D-S. (Deng-Shun), Malter, J.S. (James S)   +3 more
openaire   +4 more sources

아토피피부염 환아에서 혈청 thymic stromal lymphopoietin (TSLP) 의 증가

, 2008
Dept. of Medicine/석사[한글] 목적 : Thymic stromal lymphopoietin (TSLP)은 수지세포의 성숙과 활성화를 유도하는 싸이토카인으로, 최근 아토피피부염과의 연관성이 보고되고 있다. 본 연구에서는 혈청 TSLP의 농도가 소아의 아토피피부염을 진단하고 중증도를 평가하는 지표로 유용한지 여부와 그 의의를 알아보고자 하였다.대상 및 방법 : IgE 매개성 아토피피부염 환아 75명, 비 IgE 매개성 아토피피부염 환아가 ...
이은별
core  

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents

Scientific Reports, 2017
Mutations in the gene encoding for filaggrin (FLG) are major predisposing factors for atopic dermatitis (AD). Besides genetic predisposition, immunological dysregulations considerably contribute to its pathophysiology.
Leonie Wallmeyer, Kristina Dietert, Michaela Sochorová, Achim D. Gruber, Burkhard Kleuser, Kateřina Vávrová, Sarah Hedtrich   +6 more
doaj   +1 more source

IL-33 and Thymic Stromal Lymphopoietin in mast cell functions

, 2016
Thymic Stromal Lymphopoietin (TSLP) and Interleukin 33 (IL-33) are two cytokines released by cells that are in proximity to our environment, e.g., keratinocytes of the skin and epithelial cells of the airways.
Maria Elizabeth Ketelaar, Gunnar Nilsson, Anna Zoltowska, Ketelaar, Maria Elizabeth, Saluja, Rohit, Zoltowska, Anna, Nilsson, Gunnar, Rohit Saluja   +7 more
core   +1 more source

Effects of Quercetin Treatment on Epithelium-derived Cytokines and Epithelial Cell Apoptosis in Allergic Airway Inflammation Mice Model

Iranian Journal of Allergy, Asthma and Immunology, 2017
Quercetin is a dietary flavonoid which has anti-inflammatory effects. This study aimed to evaluate the influence of quercetin on histopathological aspects and airway epithelium in  allergic airway  inflammation mice model.
Sule Caglayan Sozmen, Meral Karaman, Serap Cilaker Micili, Sakine Isik, Alper Bagriyanik, Zeynep Arikan Ayyildiz, Nevin Uzuner, Ozden Anal, Ozkan Karaman   +8 more
doaj  

Characterizing thymic stromal lymphopoietin (TSLP): a role in neurite outgrowth

, 2014
Neuropathy is a serious complication of diabetes mellitus. In particular, sensory innervation is progressively lost as neurons degenerate distally. Many proinflammatory cytokines have been implicated in signalling through pathways that mediate nerve ...
Verrelli, Alyssa
core  

Thymic stromal lymphopoietin exerts antimicrobial activities.

, 2011
Thymic stromal lymphopoietin (TSLP) is an interleukin-7-like cytokine expressed by epithelial cells and reported to be involved in allergic diseases and atopic eczema.
Ole E. Sørensen, Martin Malmsten, Olin, Anders,, Gopinath Kasetty, Sonesson, Andreas,, Mörgelin, Matthias,, Matthias Mörgelin, Mörgelin, Matthias, Anders I. Olin, Kasetty, Gopinath, Olin, Anders, Sorensen, Ole E., Sonesson, Andreas, Andreas Sonesson, Malmsten, Martin, Schmidtchen, Artur,, Schmidtchen, Artur, Malmsten, Martin,, Sørensen, Ole E,, Sørensen, Ole E, Artur Schmidtchen, Olin, Anders I., Kasetty, Gopinath,, Lund University.   +23 more
core   +1 more source

TSLP: contrasting roles in cancer

Frontiers in Immunology
Thymic stromal lymphopoietin (TSLP) is an alarmin cytokine possessing a plethora of pleiotropic properties. Human and mouse TSLP exerts their activity via a heterodimeric complex composed of TSLP receptor (TSLPR) chain and IL-7Rα.
Remo Poto, Remo Poto, Remo Poto, Gianni Marone, Gianni Marone, Gianni Marone, Steven F. Ziegler, Steven F. Ziegler, Steven F. Ziegler, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +11 more
doaj   +1 more source

CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression

Epigenetics
Thymic Stromal Lymphopoietin (TSLP), an immunomodulatory cytokine, plays a pivotal role in the development and progression of atopic and allergic diseases.
Krishna Priya Ganti, Milan Surjit
doaj   +1 more source