Results 91 to 100 of about 139,364 (204)
Allergology International, 2013 Atopy is a phenotypically heterogeneous condition, and the extent to which atopy accounts for asthma is controversial. In this study, we aimed to identify the presence of distinct sensitization patterns to common inhaled allergens and their association with asthma, allergic rhinitis and TSLP genotypes.We studied 1683 adults from Tsukuba, a city in ...
Iijima, Hiroaki +12 more
openaire +3 more sources
Allergy, Volume 81, Issue 9, Page 3107-3129, September 2026.ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin +4 more
wiley +1 more source
IL-17A-associated IKK-α signaling induced TSLP production in epithelial cells of COPD patients
Experimental and Molecular Medicine, 2018 Lung disease: inflammatory proteins implicated in chronic obstructive pulmonary disease Two proteins involved in the maturation of immune cells contribute to the inflammation responsible for chronic obstructive pulmonary disease (COPD) and could thus ...
Giulia Anzalone +9 more
doaj +1 more source
Thymic stromal lymphopoietin (TSLP) – pro-inflammatory cytokine and antimicrobial peptide
Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchThymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine primarily produced by epithelial cells. It functions as a key regulator of immune responses, especially at barrier surfaces such as the skin, gut, and respiratory tract. Humans express two forms of TSLP: long-form TSLP (lfTSLP), which acts as a pro-inflammatory cytokine, and short-form TSLP (
Katinka, Döhner +2 more
openaire +2 more sources
Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
Allergy, Volume 81, Issue 9, Page 3261-3272, September 2026.EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
Thymic stromal lymphopoietin as a novel mediator amplifying immunopathology in rheumatic disease [PDF]
, 2015 Thymic stromal lymphopoietin (TSLP) is an IL-7-related cytokine that has been studied extensively in atopic diseases and more recently in various rheumatic disorders.
van Roon, Joel A.G. +5 more
core +1 more source
Remission in Global Airway Diseases: EUFOREA Consensus Paper
Allergy, Volume 81, Issue 9, Page 3146-3156, September 2026.ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow +22 more
wiley +1 more source
, 2021 Keratinocytes constitute the first-line barrier against exogenous antigens and contain Toll-like receptors (TLRs), which function as pattern-recognition molecules to activate antimicrobial innate immune responses. In an effort to ascertain whether or not
조경아, 우소연
core +1 more source
S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty. [PDF]
Respir Res, 2023 Gagnon PA +9 more
europepmc +1 more source
, 2021 Thymic stromal lymphopoietin (TSLP) is a pro-inflammatory cytokine with important pathological roles in Asthma bronchiale, malignant tumours and other diseases.
Marković, Iva +4 more
core +1 more source