Results 81 to 90 of about 139,364 (204)

LINFOPOYETINA ESTROMAL TÍMICA: REGULACIÓN DE LA RESPUESTA INMUNE Y LA ENFERMEDAD ALÉRGICA

Universitas Scientiarum, 2007
Recientemente se ha descrito una citocina similar a interleucina (IL) 7: Thymic Stromal Lymphopoietin (TSLP). La molécula TSLP es secretada por células epiteliales y en humanos estimula principalmente células de linaje mieloide, a diferencia del ratón ...
A. Cuéllar
doaj  

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 986-995, September 2026.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Mucosal vaccination with long-form TSLP induces migratory cDC1-mediated adaptive immunity against SARS-CoV-2 infection

Journal of Virology
A combination of vaccination strategies will potentially be required for effective control of the virus pandemic. We report that mice intranasally immunized with commercial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subunit vaccines ...
Jing Hu, Housheng Zheng, Wei Ran, Xuefei Wang, Chenghui Liao, Jian Zhou, Liang Ye   +6 more
doaj   +1 more source

TSLP and Immune Homeostasis

Allergology International, 2012
In an immune system, dendritic cells (DCs) are professional antigen-presenting cells (APCs) as well as powerful sensors of danger signals. When DCs receive signals from infection and tissue stress, they immediately activate and instruct the initiation of
Shino Hanabuchi, Norihiko Watanabe, Yong-Jun Liu   +2 more
doaj   +1 more source

Thymic Stromal Lymphopoietin-Mediated Extramedullary Hematopoiesis Promotes Allergic Inflammation [PDF]

, 2013
SummaryExtramedullary hematopoiesis (EMH) refers to the differentiation of hematopoietic stem cells (HSCs) into effector cells that occurs in compartments outside of the bone marrow.
Cianferoni, Antonella, Kim, Brian S., Osborne, Lisa C., Tait Wojno, Elia D., Benitez, Alain J., Hakonarson, Hakon, Ruymann, Kathryn R., Saenz, Steven A., Sleiman, Patrick M., Wang, Mei-Lun, Spergel, Jonathan M., Comeau, Michael R., Artis, David, Farber, Donna L., Ziegler, Carly G., Siracusa, Mark C.   +15 more
core   +1 more source

Skin tissue expression and serum level of thymic stromal lymphopoietin in patients with psoriasis vulgaris

Dermatology Reports, 2019
Thymic stromal lymphopoietin (TSLP) is known to be associated with allergic diseases. It is also suggested that TSLP has a role in autoimmune diseases such as psoriasis; however, the associated pathways remain unknown.
Oki Suwarsa, Hartati Purbo Dharmadji, Endang Sutedja, Lengga Herlina, Putri Reno Sori, Reti Hindritiani, Reiva Farah Dwiyana, Hendra Gunawan   +7 more
doaj   +1 more source

Herbal Extracts and Plant‐Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Food‐derived bioactives, herbal extracts, and standardized botanical products are being investigated as adjunctive strategies for atopic dermatitis. Their biological activity is shaped not only by plant source and nominal dose, but also by fermentation, drying, heating, extraction, food‐matrix binding, gastrointestinal transformation, and formulation ...
Muhuang Zeng, Qianlan Yuan, Shuojia Huang, Xiaofei Lu   +3 more
wiley   +1 more source

Thymic Stromal Lymphopoietin Is Produced by Dendritic Cells

, 2011
Thymic stromal lymphopoietin (TSLP) is a type 1 cytokine that contributes to lymphopoiesis and the development of asthma and atopic dermatitis. TSLP acts on multiple lineages, including dendritic cells (DCs), T cells, NKT cells, eosinophils, and mast ...
Mohit Kashyap, Leigh Samsel, Rosanne Spolski, Warren J. Leonard, Yrina Rochman   +4 more
core   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, Volume 81, Issue 9, Page 3345-3360, September 2026.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Cellular and Molecular Mechanisms of TSLP Function in Human Allergic Disorders - TSLP Programs the “Th2 code” in Dendritic Cells

Allergology International, 2012
Thymic stromal lymphopoietin (TSLP) has been recently implicated as a key molecule for initiating allergic inflammation at the epithelial cell-dendritic cell (DC) interface.
Tomoki Ito, Yong-Jun Liu, Kazuhiko Arima
doaj   +1 more source