Results 101 to 110 of about 152,280 (211)

Thymic Stromal Lymphopoietin (TSLP)

Current allergy and asthma reports
Purpose of the Review: Thymic stromal lymphopoietin (TSLP) is increasingly recognized for its pivotal role in the pathogenesis of various epithelial-driven chronic inflammatory diseases. This review navigates the existing evidence on TSLP, with a particular focus on asthma, before delving into the current understanding of its role in chronic ...
de Corso, Eugenio, Hellings, Peter W., Fokkens, Wytske J., Klimek, Ludger, Peters, Anju T., Scadding, Glenis K., Desrosiers, Martin, Lee, Stella E., Mullol, Joaquim   +8 more
openaire   +1 more source

Functions of thymic stromal lymphopoietin in immunity and disease

, 2012
Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine expressed mainly by epithelial cells. Current studies provide compelling evidence that TSLP is capable of activating dendritic cells to promote T helper (Th) 2 immune responses.
Baohua Zhou, Zhang, Yanlu, Zhou, Baohua, Yanlu Zhang   +3 more
core   +1 more source

Serum thymic stromal lymphopoietin (TSLP) levels in atopic dermatitis patients: a systematic review and meta-analysis. [PDF]

Clin Exp Med, 2023
García-Reyes MM, Zumaya-Pérez LC, Pastelin-Palacios R, Moreno-Eutimio MA.   +3 more
europepmc   +1 more source

Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway

Biomolecules
Disruption of the airway epithelium triggers a defensive immune response that begins with the production and release of alarmin cytokines. These epithelial-derived alarmin cytokines, including thymic stromal lymphopoietin (TSLP), are produced in response
Danica L. Brister, Hafsa Omer, Christiane E. Whetstone, Maral Ranjbar, Gail M. Gauvreau   +4 more
doaj   +1 more source

Successful Treatment of Eosinophilic Chronic Rhinosinusitis and Secretory Otitis Media in Refractory Asthma With Thymic Stromal Lymphopoietin (TSLP) Receptor Monoclonal Antibody. [PDF]

Cureus, 2023
Kawashima K, Matsuno O, Okuno M, Kawabe T, Hanada Y.   +4 more
europepmc   +1 more source

Thymic Stromal Lymphopoietin Induces Migration in Human Airway Smooth Muscle Cells [PDF]

, 2014
Airway remodeling due to increased airway smooth muscle (ASM) mass, likely due to enhanced migration and proliferation, has been shown to be highly associated with decline in lung function in asthma.
Shan, Lianyu, Gounni, Abdelilah S., Movassagh, Hesam, Redhu, Naresh   +3 more
core   +1 more source

Evaluating the Impact of Prior Sponge and Lavage Sampling on Gene Expression of Nasal CMA1 and TSLP Collected With Brush

Clinical &Experimental Allergy, EarlyView.
Abigail Davis, Sophie Spicer, Lubnaa Hossenbaccus, Anne K. Ellis   +3 more
wiley   +1 more source

A New Itch to Scratch for TSLP

, 2014
Atopic dermatitis (AD) is characterized by allergic inflammation and itch. Thymic stromal lymphopoietin (TSLP) is a pro-allergic cytokine implicated in AD.
Zhou, Baohua, Turner, Matthew J.
core   +1 more source

A dual computational and experimental strategy to enhance TSLP antibody affinity for improved asthma treatment.

PLoS Computational Biology
Thymic stromal lymphopoietin is a key cytokine involved in the pathogenesis of asthma and other allergic diseases. Targeting TSLP and its signaling pathways is increasingly recognized as an effective strategy for asthma treatment.
Yitong Lv, He Gong, Xuechao Liu, Jia Hao, Lei Xu, Zhiwei Sun, Changyuan Yu, Lida Xu   +7 more
doaj   +1 more source

Benralizumab Inhibits Upper Airway Expression of Thymic Stromal Lymphopoietin in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Hazel Marriott, Marc Duchesne, Jalal Moolji, Adil Adatia, Subhabrata Moitra, Paige Lacy   +5 more
wiley   +1 more source