Results 121 to 130 of about 152,280 (211)

Effects of Quercetin Treatment on Epithelium-derived Cytokines and Epithelial Cell Apoptosis in Allergic Airway Inflammation Mice Model

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2017
Quercetin is a dietary flavonoid which has anti-inflammatory effects. This study aimed to evaluate the influence of quercetin on histopathological aspects and airway epithelium in  allergic airway  inflammation mice model.
Sule Caglayan Sozmen   +8 more
doaj  

Thymic stromal lymphopoietin exerts antimicrobial activities.

open access: yes, 2011
Thymic stromal lymphopoietin (TSLP) is an interleukin-7-like cytokine expressed by epithelial cells and reported to be involved in allergic diseases and atopic eczema.
Ole E. Sørensen   +23 more
core   +1 more source

Thymic Stromal Lymphopoietin and Tezepelumab in Airway Diseases: From Physiological Role to Target Therapy

open access: yes
Thymic stromal lymphopoietin (TSLP), is a protein belonging to a class of epithelial cytokines commonly called alarmins, which also includes IL-25 and IL-33. Functionally, TSLP is a key player in the immune response to environmental insults, initiating a
Braido, Fulvio   +13 more
core   +1 more source

CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression

open access: yesEpigenetics
Thymic Stromal Lymphopoietin (TSLP), an immunomodulatory cytokine, plays a pivotal role in the development and progression of atopic and allergic diseases.
Krishna Priya Ganti, Milan Surjit
doaj   +1 more source

Potential of alarmin-targeted bispecific and combination therapies in airway disease

open access: yesFrontiers in Allergy
Thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 are epithelial-derived proinflammatory alarmin cytokines that drive inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD).
H. Kiyomi Komori, Hector Ortega
doaj   +1 more source

Thymic stromal lymphopoietin-induced HOTAIR activation promotes endothelial cell proliferation and migration in atherosclerosis

open access: yes, 2017
Endothelial cells’ (EC) injury is a major step for the pathological progression of atherosclerosis. Recent study demonstrated that thymic stromal lymphopoietin (TSLP) exerts a protective role in atherosclerosis.
Yin Lan   +7 more
core   +1 more source

Research progress on the application of thymic stromal lymphopoietin monoclonal antibody in the treatment of severe asthma

open access: yesNeike lilun yu shijian
This article reviews the research progress on tezepelumab, an anti-thymic stromal lymphopoietin (TSLP) monoclonal antibody, in the treatment of severe asthma.
Min ZHANG, Xiankun DENG
doaj   +1 more source

Discovery of Natural Dual Inhibitors from ZINC Database Targeting Thymic Stromal Lymphopoietin (TSLP) and Interleukin-33 (IL-33) as Potential Anti-Allergy Agents - MD Simulation XVG Files and Complex PDB Files (Docking Results)

open access: yes
<p>This repository contains XVG files representing both unbound and ligand-bound complexes of TSLP and IL33 proteins (Output of MD Simualtions). Additionally, it includes the PDB files corresponding to these complexes for both TSLP and IL33 (Output
Jayaraman, Muthukumaran   +4 more
core   +2 more sources

Study of the role of the thymic stromal lymphopoietin (TSLP) in the atopic march

open access: yes
Etude du rôle de la cytokine thymic stromal lymphopoietin (TSLP) produite par les keratinocytes dans la marche atopique La marche atopique désigne la progression séquentielle des maladies atopiques, en particulier l’apparition d’asthme chez les enfants précédée par celle d’une dermatite atopique (DA) sévère chez les nourrissons. De plus,
openaire   +1 more source

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