Results 131 to 140 of about 12,710 (220)

Dimeric procyanidins as modulators of airway inflammation in the context of allergic asthma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Human Physiology at Massey University, Manawatū, Palmerston North, New Zealand [PDF]

, 2017
Procyanidins are polyphenolic compounds that have come to be known as biologically active in the context of promoting human health. Epidemiological evidence suggests that populations that consume diets rich in procyanidins are less susceptible to ...
Coleman, Sara L
core  

Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. [PDF]

, 2019
Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics.
Broide, David H, Hur, Gyu Young
core  

Effects of Quercetin Treatment on Epithelium-derived Cytokines and Epithelial Cell Apoptosis in Allergic Airway Inflammation Mice Model

Iranian Journal of Allergy, Asthma and Immunology, 2017
Quercetin is a dietary flavonoid which has anti-inflammatory effects. This study aimed to evaluate the influence of quercetin on histopathological aspects and airway epithelium in  allergic airway  inflammation mice model.
Sule Caglayan Sozmen, Meral Karaman, Serap Cilaker Micili, Sakine Isik, Alper Bagriyanik, Zeynep Arikan Ayyildiz, Nevin Uzuner, Ozden Anal, Ozkan Karaman   +8 more
doaj  

TSLP: contrasting roles in cancer

Frontiers in Immunology
Thymic stromal lymphopoietin (TSLP) is an alarmin cytokine possessing a plethora of pleiotropic properties. Human and mouse TSLP exerts their activity via a heterodimeric complex composed of TSLP receptor (TSLPR) chain and IL-7Rα.
Remo Poto, Remo Poto, Remo Poto, Gianni Marone, Gianni Marone, Gianni Marone, Steven F. Ziegler, Steven F. Ziegler, Steven F. Ziegler, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +11 more
doaj   +1 more source

Risk factors for inflammatory obstructive pulmonary diseases: a prospective cohort study [PDF]

, 2013
科学研究費助成事業(科学研究費補助金)研究成果報告書：基盤研究(C)2010-2012課題番号 ...
Sakamoto Tohru, 坂本 透
core  

Potential of alarmin-targeted bispecific and combination therapies in airway disease

Frontiers in Allergy
Thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 are epithelial-derived proinflammatory alarmin cytokines that drive inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD).
H. Kiyomi Komori, Hector Ortega
doaj   +1 more source

Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development

, 2019
In mammals, T cell development critically depends on the IL-7 cytokine signaling pathway. Here we describe the identification of the zebrafish ortholog of mammalian IL-7 based on chromosomal localization, deduced protein sequence, and expression patterns.
Boehm, T., Hess, I., Iwanami, N., Lawir, D., Schorpp, M., Siamishi, I., Sikora, K.   +6 more
core   +1 more source

Thymic stromal lymphopoietin (TSLP) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Disrupting TSLP–TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases

EMBO Molecular Medicine
Thymic stromal lymphopoietin (TSLP) is a key player in atopic diseases, which has sparked great interest in therapeutically targeting TSLP. Yet, no small-molecule TSLP inhibitors exist due to the challenges of disrupting the protein–protein interaction ...
Partho Protim Adhikary, Temilolu Idowu, Zheng Tan, Christopher Hoang, Selina Shanta, Malti Dumbani, Leah Mappalakayil, Bhuwan Awasthi, Marcel Bermudez, January Weiner, Dieter Beule, Gerhard Wolber, Brent DG Page, Sarah Hedtrich   +13 more
doaj   +1 more source

Distinct Roles for Thymic Stromal Lymphopoietin (TSLP) and IL-33 in Experimental Eosinophilic Esophagitis. [PDF]

Allergy
Dsilva A, Wagner A, Itan M, Rhone N, Avlas S, Gordon Y, Davidian N, Sharma S, Razravina E, Zan-Bar I, Parnes JR, Gorski KS, Sherrill JD, Varol C, Ziegler SF, Rothenberg ME, Munitz A.   +16 more
europepmc   +1 more source