Results 121 to 130 of about 127,095 (220)

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li   +23 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

open access: yesChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee   +4 more
wiley   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1335-1341, March 2026.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi   +3 more
wiley   +1 more source

Prognostic performance of thymidine kinase 1 activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with CDK4/6 and aromatase inhibitors. [PDF]

open access: yesBreast Cancer Res Treat
Brown NL   +12 more
europepmc   +1 more source

Impact of Thymidine Loop Modifications on Telomeric G-Quadruplex Catalytic Systems for Asymmetric Sulfoxidation. [PDF]

open access: yesMolecules
Finamore C   +8 more
europepmc   +1 more source

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