Results 151 to 160 of about 162,084 (246)

Iodine-mediated 2,5-di(aryl/heteroaryl)-1,3,4-oxadiazoles: synthesis, and <i>in vitro</i> and <i>in silico</i> studies of anticancer and antifungal properties. [PDF]

RSC Adv
Ramesha T, Shenoy TN, Subba Reddy UV, Ega JK, Gogula SS, Swathi B, Burgula S, Reddy PM, Abdul Salam AA.   +8 more
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, EarlyView.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

DNA replication stress and translational repression converge to drive CDK1- and caspase-dependent apoptosis in Ewing sarcoma. [PDF]

Oncogene
Koppenhafer SL, Thomas MV, Mhindu MT, Zimmerman JAO, Gordon DJ.   +4 more
europepmc   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Nuclear compartmentalization at the G1/S transition plays a key role in DNA replication control. [PDF]

Nat Commun
Oji A, Yusa K, Noda I, Ichinose T, Kondo Y, Hiratani I.   +5 more
europepmc   +1 more source

From Association to Mechanism: Regulatory Annotation and Pathway Mapping of Genes Surrounding Breast Cancer Risk Variants

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Inherited factors account for a large share of breast cancer susceptibility, yet the biological consequences of most risk variants are still poorly understood. To address this gap, we studied 175 breast cancer risk variants confirmed by genome‐wide association studies and gathered the genes that lie near them.
Sultana Jannat, Trina Mitra, Nafisa Nawar Fariha, Tasmia Tabassum, Kulsuma Bahar Bethi, Synchita Majumder Kaya, Md. Arif Hossen, Md. Saad Hossain, Jobaier Ibne Deen, Mohammed Emon, Laila Khaleda, Md. Hridoy Ahmed   +11 more
wiley   +1 more source

Petromaroside A, an unprecedented natural nucleoside from the sponge <i>Petrosia</i> sp. with potent cytotoxicity and biosynthetic insight. [PDF]

RSC Adv
Luu PV, Ton-Nu HL, Nguyen HM, Nguyen CQ, Thai QM, Lai KH.   +5 more
europepmc   +1 more source

Feasibility of multi‐energy CT and fat fraction MRI for characterizing active bone marrow response to pelvic external beam radiation therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background Pelvic external beam radiation therapy (EBRT), frequently exposes a substantial fraction of active bone marrow (ABM), leading to radiation‐induced marrow suppression and associated hematologic toxicity. Accurate delineation and quantitative assessment of ABM are therefore essential to enable marrow‐sparing radiotherapy strategies ...
Carolyn Eckrich, Kristin Bradley, Bethany Anderson, Diego Hernando, Jessica Miller, Jainil Shah, Patrick Wohlfahrt, Michael Lawless   +7 more
wiley   +1 more source

Physiological re-replication during human stem cell differentiation. [PDF]

Cell Death Discov
Minet M, Beganovic A, Rishik S, Michaeli E, Yildiz D, Schmartz GP, Schwarz PE, Schäfer M, Tänzer T, Cucchiarini M, Ludwig N, Keller A, Meese E, Fischer U.   +13 more
europepmc   +1 more source

Thymic Involution and Function in People With HIV and General Population Controls: A Cross‐Sectional Analysis From Two Danish Cohort Studies

Aging Cell, Volume 25, Issue 10, October 2026.
Thymic involution, the age‐related replacement of thymic soft tissue by fat, has been linked to immunosenescence and chronic inflammation. Whether HIV infection affects thymic involution remains unclear. We found that people with HIV on long‐term antiretroviral therapy had more thymic tissue than controls, indicating less thymic involution. More thymic
Manon C. Vanbellinghen, Anders Boyd, Andreas Ohrt Johansen, Moises Alberto Suarez‐Zdunek, Andreas Dehlbæk Knudsen, Thomas Skårup Kristensen, Jørgen Tobias Kühl, Per Ejlstrup Sigvardsen, Michael Huy Cuong Pham, Andreas Fuchs Larsen, Klaus Fuglsang Kofoed, Børge Grønne Nordestgaard, Shoaib Afzal, Neeltje Kootstra, Susanne Dam Nielsen, Peter Reiss   +15 more
wiley   +1 more source