Results 161 to 170 of about 162,084 (246)
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz +8 more
wiley +1 more source
Association between thymidine kinase 1 and clinicopathological high-risk features in breast cancer. [PDF]
Medicine (Baltimore)Liu Y, Liu J.
europepmc +1 more source
To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy
European Journal of Haematology, Volume 117, Issue 4, Page 750-766, October 2026.ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino +16 more
wiley +1 more source
Fully Reversible Regulation of 8‐17 DNAzyme Activity Using Nucleoside‐Based Diarylethenes
Chemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.The site‐specific incorporation of nucleosidic diarylethenes into the 8–17 deoxyribozyme (DNAzyme) identified position 2.1 as optimal. Compound dU‐PhtBu enabled efficient light‐dependent control of catalytic activity, while maintaining thermal stability and reversibility.
Jörn Bargstedt +3 more
wiley +1 more source
SYNTHESIS OF 1-SUBSTITUTED ANALOGS OF THYMIDINE.
, 1960 SYNTHESIS OF 1-SUBSTITUTED ANALOGS OF ...
ROBERT CHARLES. SMITH (7973903)
core
On the Calculations of Electron Impact Ionization Cross-Sections for Selected Nucleosides and Deoxyribose Molecules. [PDF]
MoleculesMożejko P.
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Transcriptomic and metabolomic profiling of Ornithodoros lahorensis during African swine fever virus (ASFV) infection reveals that ASFV rewires host purine/pyrimidine metabolism, lipid metabolism, and energy metabolism. A core gene‐metabolite regulatory axis consisting of 12 key genes and 8 signature metabolites is identified to support viral genome ...
Jin Luo +9 more
wiley +1 more source
Re-evaluation of bovine herpesvirus 4 genotyping based on the thymidine kinase gene. [PDF]
J VirolLu W, Pu J, Luo J, Zhang S, Cao J, Ma C.
europepmc +1 more source
Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier +7 more
wiley +1 more source
Helical Folding of Abiotic Chiral Poly(phosphodiester)s
Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.Design and structural analysis of a new class of phosphodiester foldamers are presented. These oligomers that fold into single helical architecture showed length and temperature stability dependence comparable to DNA duplexes. ABSTRACT Functions of biomolecules are intimately linked to their structures which result from the folding of a linear sequence
Ranajit Barman +3 more
wiley +1 more source