SYNTHESIS, CHARACTERIZATION AND APPLICATIONS OF NOVEL AMPHIPHILIC DERIVATIVES OF NUCLEOSIDES
In a first part of my work, preliminary to all the successive investigations, novel thymidine- or uridine-based nucleolipids, containing one hydrophilic oligo(ethylene glycol) chain and one or two oleic acid residues (called ToThy, HoThy, DoHu and ...
Simeone, Luca
core
Enzyme-Responsive Cyclic Gapmer Antisense Oligonucleotides via Thymidine <i>C</i>5-<i>C</i>5 Cross-Linking within the Gap Region Using a Galactosylated Branched Self-Immolative Linker. [PDF]
Miyaji K, Habu N, Seio K.
europepmc +1 more source
Light‐Activated Nucleic Acid Amplification Systems Using Photo‐Caged DNA Polymerase or Primers
ABSTRACT Precise control over nucleic acid amplification is essential for achieving reliable, quantitative, high‐throughput, and multiplexed molecular diagnostics, particularly in point‐of‐care and field settings. However, conventional isothermal amplification methods, especially rapid assays at ambient temperature such as recombinase‐aided ...
Yang Wu +20 more
wiley +1 more source
DCTPP1 orchestrates dCTP pool dynamics and mtDNA stability in quiescent cells. [PDF]
Fernández B +5 more
europepmc +1 more source
Neuroglia have been extensively profiled using single‐cell genomics, improving our understanding of their dynamics after spinal cord injury. A meta‐analysis of five single‐cell time‐course genomic studies reveals heterogeneity underscoring important challenges for interpretation.
Julio Mejia, Philip J. Horner
wiley +1 more source
TK1 in gastric cancer: Helicobacter pylori-driven oncogenesis biomarker, utility, and emerging targeted therapies. [PDF]
Zheng ZX +5 more
europepmc +1 more source
Mechanistic Studies on DNA Damage via Independent Generation of Purine Reactive Intermediates. [PDF]
Zheng L, Greenberg MM.
europepmc +1 more source
Quantifying Epigenetic Changes Induced by Chemical Exposure Using the epi-TK Assay. [PDF]
Kuroki S +5 more
europepmc +1 more source
Identification of Natural and Artificial Modifications in DNA at the Nanometer Level
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig +4 more
wiley +1 more source
Correction: PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression. [PDF]
Teye EK +9 more
europepmc +1 more source

