On the Calculations of Electron Impact Ionization Cross-Sections for Selected Nucleosides and Deoxyribose Molecules. [PDF]
Możejko P.
europepmc +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
Characterization of Gastrointestinal Absorption of Salmon Milt-Derived Oligodeoxyribonucleic Acids in Mice. [PDF]
Hayashi F +8 more
europepmc +1 more source
Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia +5 more
wiley +1 more source
Synthesis, characterization, <i>in vitro</i> and <i>in silico</i> studies of novel lophine clubbed acylthioureas. [PDF]
Ullah SA +10 more
europepmc +1 more source
Real‐World Efficacy of Metronomic Chemotherapy in Advanced Breast Cancer Across Molecular Subtypes
ABSTRACT Objective Metronomic chemotherapy (mCHT) is widely used in the treatment of breast cancer due to its low toxicity and convenience. However, there remain real‐world studies with satisfactory samples focusing on mCHT in advanced breast cancer. Methods Enrolled patients were assigned into capecitabine‐based (X‐based) group and other mCHT group ...
Hanxing Zhou +6 more
wiley +1 more source
The dynamics of centromere assembly and disassembly during quiescence. [PDF]
Marescal O +4 more
europepmc +1 more source
Boronic acid‐substituted thymine derivatives are well established and exhibit a range of biological activities. In contrast, the corresponding boronic acid esters and dioxazaborocane analogs remain largely unexplored. Herein, we report the synthesis and structural characterization of thymine derivatives bearing boronic acid, boronic acid ester, and ...
Tabea Lenz +2 more
wiley +1 more source
The effects of high-intensity interval training versus continuous moderate-intensity exercise on body composition among older adults with HIV. [PDF]
Kulik GL +10 more
europepmc +1 more source
Molecular weight and charge of polysaccharides dictate the microbial utilization efficiency of selenium nanoparticles. Chitosan‐based selenium nanoparticles optimize Se metabolism and gut health via specific microbial enrichment. ABSTRACT Selenium (Se) exists in various chemical forms, including inorganic Se, organic Se, and Se nanoparticles (SeNPs ...
Meiyu Yuan +6 more
wiley +1 more source

