Results 171 to 180 of about 151,356 (287)

Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy

open access: yesAggregate, Volume 7, Issue 6, June 2026.
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao   +5 more
wiley   +1 more source

Characterization of Gastrointestinal Absorption of Salmon Milt-Derived Oligodeoxyribonucleic Acids in Mice. [PDF]

open access: yesJ Nutr Metab
Hayashi F   +8 more
europepmc   +1 more source

Heterogenous Model of Temozolomide Resistance in Glioblastoma Reveals Phenotypic Shifts in Drug Response and Migratory Potential

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia   +5 more
wiley   +1 more source

Synthesis, characterization, <i>in vitro</i> and <i>in silico</i> studies of novel lophine clubbed acylthioureas. [PDF]

open access: yesRSC Adv
Ullah SA   +10 more
europepmc   +1 more source

Real‐World Efficacy of Metronomic Chemotherapy in Advanced Breast Cancer Across Molecular Subtypes

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Objective Metronomic chemotherapy (mCHT) is widely used in the treatment of breast cancer due to its low toxicity and convenience. However, there remain real‐world studies with satisfactory samples focusing on mCHT in advanced breast cancer. Methods Enrolled patients were assigned into capecitabine‐based (X‐based) group and other mCHT group ...
Hanxing Zhou   +6 more
wiley   +1 more source

The dynamics of centromere assembly and disassembly during quiescence. [PDF]

open access: yesJ Cell Biol
Marescal O   +4 more
europepmc   +1 more source

Functionalizing Nucleobases With Boronic Acids and Boronic Acid Esters: Thymine Derivatives and Their Dioxazaborocane Chemistry

open access: yesChemPlusChem, Volume 91, Issue 6, June 2026.
Boronic acid‐substituted thymine derivatives are well established and exhibit a range of biological activities. In contrast, the corresponding boronic acid esters and dioxazaborocane analogs remain largely unexplored. Herein, we report the synthesis and structural characterization of thymine derivatives bearing boronic acid, boronic acid ester, and ...
Tabea Lenz   +2 more
wiley   +1 more source

The effects of high-intensity interval training versus continuous moderate-intensity exercise on body composition among older adults with HIV. [PDF]

open access: yesJ Gerontol A Biol Sci Med Sci
Kulik GL   +10 more
europepmc   +1 more source

Investigation Into the Variations in the Interactions Between Different Selenium Sources and Gut Microbiota

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Molecular weight and charge of polysaccharides dictate the microbial utilization efficiency of selenium nanoparticles. Chitosan‐based selenium nanoparticles optimize Se metabolism and gut health via specific microbial enrichment. ABSTRACT Selenium (Se) exists in various chemical forms, including inorganic Se, organic Se, and Se nanoparticles (SeNPs ...
Meiyu Yuan   +6 more
wiley   +1 more source

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