Results 31 to 40 of about 232,266 (302)
Environmental Research Letters, 2013 We compared planktonic primary and secondary production across twenty meltwater ponds on the surface of the McMurdo Ice Shelf in January 2007, including some ponds with basal brines created by meromictic stratification.
Brian K Sorrell, Ian Hawes, Karl Safi
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Deoxycytidine and deoxythymidine treatment for thymidine kinase 2 deficiency
Annals of Neurology, 2017 Thymidine kinase 2 (TK2), a critical enzyme in the mitochondrial pyrimidine salvage pathway, is essential for mitochondrial DNA (mtDNA) maintenance. Mutations in the nuclear gene, TK2, cause TK2 deficiency, which manifests predominantly in children as ...
C. López-Gómez +8 more
semanticscholar +1 more source
Clinical and biochemical improvements in a patient with MNGIE following enzyme replacement. [PDF]
, 2013 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive metabolic disorder caused by a deficiency of thymidine phosphorylase (TP, EC2.4.2.4) due to mutations in the nuclear gene TYMP.
Bax, BE +13 more
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Beilstein Journal of Organic Chemistry, 2020 In the present work, we suggested anion exchange resins in the phosphate form as a source of phosphate, one of the substrates of the phosphorolysis of uridine, thymidine, and 1-(β-ᴅ-arabinofuranosyl)uracil (Ara-U) catalyzed by recombinant E. coli uridine
Julia N. Artsemyeva +7 more
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Assessment of Thymidine Phosphorylase Function: Measurement of Plasma Thymidine (and Deoxyuridine) and Thymidine Phosphorylase Activity [PDF]
, 2011 We describe detailed methods to measure thymidine (dThd) and deoxyuridine (dUrd) concentrations and thymidine phosphorylase (TP) activity in biological samples. These protocols allow the detection of TP dysfunction in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Martí R, López LC, Hirano M.
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Human Keratinocytes Catabolize Thymidine [PDF]
, 1988 Human neonatal foreskin keratinocytes incorporate exogenous thymidine into DNA and proliferate in vitro even after reaching confluence. Keratinocytes also catabolize thymidine, as reported for the first time below.
Kugelman, Lisa C. +4 more
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Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine. [PDF]
PLoS ONE, 2017 Thymidine kinase converts 5-fluorodeoxyuridine to 5-fluorodeoxyuridine monophosphate, which causes disruption of deoxynucleotide triphosphate ratios.
Hossain Mohammad Shamim +5 more
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THE RING STRUCTURE OF THYMIDINE
Journal of Biological Chemistry, 1935 The 2-desoxy-ribose nucleosides, first isolated by Levene and London’ by the hydrolysis of thymus nucleic acid, are characterized by their extreme ease of hydrolysis by very dilute mineral acids. Thus, guanine-2-desoxy-riboside is completely hydrolyzed by heating with 0.01 N hydrochloric acid during 5 minutes.
P A, Levene, R S, Tipson
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Optimisation of the lymphocyte proliferation assay in rainbow trout (Oncorhynchus mykiss)
Veterinární Medicína, 2019 The lymphocyte proliferation assay is a valuable method used for the evaluation of the fish immune system. However, there are many variations and optimal results are not always obtained.
Hana Minarova +6 more
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THYMIDINE DEGRADATION PRODUCTS IN PLANT TISSUES LABELED WITH TRITIATED THYMIDINE [PDF]
The Journal of Cell Biology, 1963 A study of the metabolic pathways of H3-thymidine utilization in buds of Lilium longiflorum and root tips of Vicia faba was undertaken in order to obtain information that might explain the binding of H3 from H3-thymidine in the cytoplasm of these plants.
S T, TAKATS, R M, SMELLIE
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