Results 41 to 50 of about 232,266 (302)

Bacteria abundance, thymidine incorporation of station EN198_3-2 [PDF]

open access: yes, 2003
Bacteria abundance, thymidine incorporation of station EN198_7-
Ducklow, Hugh W   +1 more
core   +1 more source

Hydrogen Peroxide-Induced Thymidine Incorporation Into Cultured Rat Astrocytes

open access: yesJournal of Pharmacological Sciences, 2006
We characterized [methyl-3H]thymidine ([3H]thymidine) and [5-3H]uridine ([3H]uridine) incorporation into cultured astrocytes and neurons in the presence and absence of hydrogen peroxide (H2O2) in order to define the response to oxidative stress in the ...
Koh-ichi Tanaka   +3 more
doaj   +1 more source

Can plasma antioxidants prevent DNA damage in oxidative stress condition induced by growth hormone deficiency? A pilot study.

open access: yesPLoS ONE, 2021
Adult growth hormone deficiency (GHD), a condition characterized by increased oxidative stress, is related to augmented cardiovascular, metabolic and oncological risk. A case-control observational study has been performed to evaluate DNA oxidative damage
Antonio Mancini   +8 more
doaj   +1 more source

Validation of an Immunoassay for Anti-thymidine Phosphorylase Antibodies in Patients with MNGIE Treated with Enzyme Replacement Therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metabolic ...
Michelle Levene   +5 more
doaj   +1 more source

Incorporation of thymidine into onion root meristematic cell nuclei in presence of hydroxyurea and its role in recovery of mitotic activity

open access: yesActa Societatis Botanicorum Poloniae, 2015
Hydroxyurea treatment of onion roots induced mitotic block which was released by transfer of bulbs to water, and also to some extent by addition of cold or 3H-thymidine to hydroxyurea solutions.
H. Habdas
doaj   +1 more source

Inhibitory Effect of Bridged Nucleosides on Thermus aquaticus DNA Polymerase and Insight into the Binding Interactions. [PDF]

open access: yesPLoS ONE, 2016
Modified nucleosides have the potential to inhibit DNA polymerases for the treatment of viral infections and cancer. With the hope of developing potent drug candidates by the modification of the 2',4'-position of the ribose with the inclusion of a bridge,
Sung-Kun Kim   +5 more
doaj   +1 more source

Comparison of [3H]-Thymidine, Carboxyfluorescein Diacetate Succinimidyl Ester and Ki-67 in Lymphocyte Proliferation

open access: yesFrontiers in Pediatrics, 2022
BackgroundPatients with T cell deficiency <10% of normal proliferation are indicated to receive immune reconstruction by hematopoietic stem cell transplantation (HSCT).
Hsin-Ju Lee   +13 more
doaj   +1 more source

EFFECTS OF INTESTINALLY ABSORBED THYMIDINE ON TRITIATED THYMIDINE UTILIZATION

open access: yesCell Proliferation, 1979
ABSTRACTExperimental evidence presented suggests that [3H]TdR can be rapidly and efficiently transported from the intestine to the systemic circulation. This pathway for thymidine transport may be physiologically important since administration of cold thymidine in the drinking water enhances the utilization of a parenterally injected dose of [3H]TdR in
R P, Williams, I L, Cameron, E K, Adrian
openaire   +2 more sources

Transition State Analysis of Thymidine Hydrolysis by Human Thymidine Phosphorylase [PDF]

open access: yesJournal of the American Chemical Society, 2010
Human thymidine phosphorylase (hTP) is responsible for thymidine (dT) homeostasis, and its action promotes angiogenesis. In the absence of phosphate, hTP catalyzes a slow hydrolytic depyrimidination of dT yielding thymine and 2-deoxyribose (dRib).
Phillip A, Schwartz   +2 more
openaire   +2 more sources

Preparation of Tritium-Labeled Thymidine [PDF]

open access: yes, 1957
1) De la thymidine est marquée avec du tritium par échange avec les hydrogènes d'eau tritiée à 100°C pendant 24 heures en présence de catalyseur d'Adams réduit; 2) Les tritiums labiles sont éliminés à chaud dans une solution aqueuse de NaOH.
Verly, Walter, Hunebelle, G.
core   +1 more source

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