Results 41 to 50 of about 151,356 (287)
THE RING STRUCTURE OF THYMIDINE
Journal of Biological Chemistry, 1935 The 2-desoxy-ribose nucleosides, first isolated by Levene and London’ by the hydrolysis of thymus nucleic acid, are characterized by their extreme ease of hydrolysis by very dilute mineral acids. Thus, guanine-2-desoxy-riboside is completely hydrolyzed by heating with 0.01 N hydrochloric acid during 5 minutes.
P A, Levene, R S, Tipson
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EFFECTS OF INTESTINALLY ABSORBED THYMIDINE ON TRITIATED THYMIDINE UTILIZATION
Cell Proliferation, 1979 ABSTRACTExperimental evidence presented suggests that [3H]TdR can be rapidly and efficiently transported from the intestine to the systemic circulation. This pathway for thymidine transport may be physiologically important since administration of cold thymidine in the drinking water enhances the utilization of a parenterally injected dose of [3H]TdR in
R P, Williams, I L, Cameron, E K, Adrian
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Transition State Analysis of Thymidine Hydrolysis by Human Thymidine Phosphorylase [PDF]
Journal of the American Chemical Society, 2010 Human thymidine phosphorylase (hTP) is responsible for thymidine (dT) homeostasis, and its action promotes angiogenesis. In the absence of phosphate, hTP catalyzes a slow hydrolytic depyrimidination of dT yielding thymine and 2-deoxyribose (dRib).
Phillip A, Schwartz +2 more
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Preparation of Tritium-Labeled Thymidine [PDF]
, 1957 1) De la thymidine est marquée avec du tritium par échange avec les hydrogènes d'eau tritiée à 100°C pendant 24 heures en présence de catalyseur d'Adams réduit; 2) Les tritiums labiles sont éliminés à chaud dans une solution aqueuse de NaOH.
Verly, Walter, Hunebelle, G.
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PLoS ONE, 2020 Bacterial production has been often estimated from DNA synthesis rates by using tritium-labeled thymidine. Some bacteria species cannot incorporate extracellular thymidine into their DNA, suggesting their biomass production might be overlooked when using
Kenji Tsuchiya +8 more
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, 2019 The relaxation dynamics of thymine and its derivatives thymidine and thymidine monophosphate were studied using time-resolved photoelectron spectroscopy applied to a water microjet. Two absorption bands were studied, the first is a bright ππ* state which
Erica, Liu +5 more
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, 2004 Thymidine phosphorylase (platelet-derived-endothelial-cell-growth-factor) catalyzes the reversible phosphorolysis of thymidine to thymine and 2-deoxyribose-1-phosphate, activates 5′-deoxy-5-fluorouridine (5′DFUR) and inactivates trifluorothymidine (TFT).
Van Capel, Toni +6 more
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Frontiers in PharmacologyIntroductionTo evaluate the anti-cardiomyopathic activity of thymine (Thy) and to elucidate its mechanism of action.MethodsTransgenic zebrafish with enhanced green fluorescent protein (EGFP)-labelled hearts (Tg (cmlc2: EGFP)) and wild-type AB zebrafish ...
Bin Li +13 more
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Thymidine phosphorylase in cancer; Enemy or friend?
, 2016 Thymidine phosphorylase (TP) is a nucleoside metabolism enzyme that plays an important role in the pyrimidine pathway.TP catalyzes the conversion of thymidine to thymine and 2-deoxy-α-D-ribose-1-phosphate (dRib-1-P). Although this reaction is reversible,
Osman, Nemer +4 more
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Thymidine Metabolism in Neurospora crassa [PDF]
, 1968 The metabolism of thymidine by Neurospora crassa was investigated after radioactive labeling experiments showed that thymidine is not specifically incorporated into the DNA of Neurospora; a finding in contrast to the results of labeled thymidine ...
Williams, Larry Gale
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