Results 81 to 90 of about 61,976 (190)

Transcriptional effects of Organochlorine o,p′-DDT and its Metabolite p,p′-DDE in Transfected MDA-MB 231 and MCF-7 Breast Cancer Cell Lines

Research in Molecular Medicine, 2015
Background: The organochlorine DDT has estrogenic activity but the mechanism underlying the estrogenic activity of this pesticide remains unclear. In the present investigation here, we studied the transcriptional effects of a synthetic organochlorine ...
Ehsan zayerzadeh, Mohammad Kazem Koohi, Azadeh Fardipour   +2 more
doaj  

Alpha-Herpesvirus Thymidine Kinase Genes Mediate Viral Virulence and Are Potential Therapeutic Targets

Frontiers in Microbiology, 2019
Alpha-herpesvirus thymidine kinase (TK) genes are virulence-related genes and are nonessential for viral replication; they are often preferred target genes for the construction of gene-deleted attenuated vaccines and genetically engineered vectors for ...
Ying Xie, Ying Xie, Ying Xie, Liping Wu, Liping Wu, Liping Wu, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Renyong Jia, Renyong Jia, Renyong Jia, Dekang Zhu, Dekang Zhu, XinXin Zhao, XinXin Zhao, XinXin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Yin Wang, Zhiwen Xu, Zhengli Chen, Ling Zhu, Qihui Luo, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Xiaoyue Chen, Xiaoyue Chen   +50 more
doaj   +1 more source

Activin A induces ovine follicle stimulating hormone beta using -169/-58 bp of its promoter and a simple TATA box

Reproductive Biology and Endocrinology, 2009
Background Activin A increases production of follicle stimulating hormone (FSH) by inducing transcription of its beta subunit (FSHB). This induction has been studied here in LbetaT2 gonadotropes using transient expression of ovine FSHBLuc (-4741 bp of ...
Miller William L, Han Sang-oh
doaj   +1 more source

Oxygen Sensitivity of Reporter Genes: Implications for Preclinical Imaging of Tumor Hypoxia

Molecular Imaging, 2007
Reporter gene techniques have been applied toward studying the physiologic phenomena associated with tumor hypoxia, a negative prognostic indicator.
Ivana Cecic, Denise A. Chan, Patrick D. Sutphin, Pritha Ray, Sanjiv Sam Gambhir, Amato J. Giaccia, Edward E. Graves   +6 more
doaj   +1 more source

Validation of a novel HPLC-based serum thymidine kinase assay for breast cancer detection [PDF]

BioDiscovery, 2017
Elena Kuzmanova, Marilena Spanou, Emma Leckie, Nikolai Zhelev   +3 more
doaj   +3 more sources

Successful treatment of acyclovir‐resistant herpes simplex virus infection with amenamevir in a patient who received umbilical cord blood transplantation for T‐cell prolymphocytic leukemia

eJHaem
A 34‐year‐old woman received umbilical cord blood transplantation for refractory T‐cell prolymphocytic leukemia after salvage therapy with alemtuzumab.
Yuma Kawamura, Nako Uchibori, Tomoya Arakawa, Tomoki Fujii, Shuto Negishi, Shiori Morikawa, Nobuaki Fukushima, Akio Kohno, Souichi Yamada, Yoshiko Fukui, Shuetsu Fukushi, Kazutaka Ozeki   +11 more
doaj   +1 more source

Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss. [PDF]

MicroPubl Biol, 2023
Kastury N, Hidalgo V, Pandi B, Li L, Lam MPY, Lau E.   +5 more
europepmc   +1 more source

Is serum thymidine kinase 1 a prognostic biomarker in primary tumor location of colorectal carcinomas? [PDF]

Discov Oncol, 2023
Fang Y, Skog S, Ou Q, Chen Z, Liu S, Hei A, Li J, Zhou J, He E, Wan D.   +9 more
europepmc   +1 more source

Thymidine kinase 1 appears to be a marker for the prognosis of hepatocellular carcinoma based on a large-scale, multicenter study. [PDF]

J Cancer Res Clin Oncol, 2023
Jiang Y, Guo L, Han L, Li H, Li C, Wen L, Song Y, Wang Z, Wang P, Guo Q, Zhao W, Liu M, Chen J, Wu Z, Yan Y, Xu K, Gu T, Wu X, He K, Su K, Han Y.   +20 more
europepmc   +1 more source

Pearls & Oy-sters: Case Report of a Patient With Adult-Onset Thymidine Kinase 2 Gene Deficiency. [PDF]

Neurology, 2023
Morganroth J, Ljungberg L, Goldstein A, Kallish S, Asher SB, Quinn C, Price RS, Karam C.   +7 more
europepmc   +1 more source