Results 101 to 110 of about 107,915 (237)

Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes [PDF]

, 2017
Identifying mechanisms by which cells of the osteoblastic lineage communicate in vivo is complicated by the mineralised matrix that encases osteocytes, and thus, vital mechanoadaptive processes used to achieve load‐bearing integrity remain unresolved. We
Aarden, Ajubi, Alford, Bancroft, Batra, Bonewald, Brighton, Bruzzone, Burger, Burger, Burger, Chan, Cheng, Cheng, Cheng, Cheng, Cherian, Cherian, Chiba, Civitelli, Dallas, Damien, Damien, Davidson, Dietrich, Donahue, Doty, Endres, Frost, Genetos, Gluhak-Heinrich, Goldberg, Hasegawa, Heino, Iqbal, Irie, Javaheri, Javaheri, Jiang, Jones, Kamioka, Kato, Kleinnulend, Kulkarni, Lanyon, Nijweide, Osborne, Palumbo, Pitsillides, Rawlinson, Rawlinson, Rawlinson, Rawlinson, Rawlinson, Ren, Schirrmacher, Schwab, Shapiro, Siller-Jackson, Skerry, Skerry, Stanford, Su, Sugawara, Tan, Tanaka, Tanaka-Kamioka, Tatsumi, Taylor, Ulmann, Uzer, Van der Plas, Vazquez, Vezeridis, Weinbaum, Westbroek, Yamaguchi, Yang, Yellowley, You, Zaman, Zaman, Zhao, Ziambaras   +83 more
core   +3 more sources

A sulfur-containing nucleoside antibiotic from Photorhabdus

mBio
We report the discovery of 4′-thiothymidine (4′sT), a sulfur-containing nucleoside antibiotic produced by the nematode symbiont Photorhabdus asymbiotica.
Sangkeun Son, Negar Shahsavari, Thomas Privalsky, Bryson A. Hawkins, Mi-Hyun Lee, Norman Pitt, Akira Iinishi, Raleb Taher, Nikita Gupta, Chandra Sekar Shankar, Jaini Patel, Kim Lewis   +11 more
doaj   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females?

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn, Nuria Alvarez‐Sanchez, Lawrence Steinman   +2 more
wiley   +1 more source

Induction of Stress Granule Assembly is Essential for the Orchestration of DNA Damage Response [PDF]

, 2008
DNA damage provokes several responses including DNA repair, cell cycle regulation and apoptosis that collectively represent the DNA damage response (DDR).
Nicole S. Verkaik, Stephan Persengiev
core   +1 more source

Clinical and biochemical improvements in a patient with MNGIE following enzyme replacement. [PDF]

, 2013
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive metabolic disorder caused by a deficiency of thymidine phosphorylase (TP, EC2.4.2.4) due to mutations in the nuclear gene TYMP.
Bain, MD, Bax, BE, Filosto, M, Moran, N, Scarpelli, M, Tonin, P   +5 more
core   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade, Tales Alexandre Costa‐Silva, Gisele Monteiro   +2 more
wiley   +1 more source

hMENA11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2-overexpressing breast cancer cells. [PDF]

, 2015
Human Mena (hMENA), an actin regulatory protein of the ENA/VASP family, cooperates with ErbB receptor family signaling in breast cancer. It is overexpressed in high-risk preneoplastic lesions and in primary breast tumors where it correlates with HER2 ...
Circo, R, De Maria, R, Di Benedetto, A, Di Modugno, F, Matteoni, S, Melchionna, R, Mottolese, M, Nisticò, P. 1., Palermo, Belinda, Soddu, S, Spada, Sheila, Trono, P   +11 more
core   +2 more sources

The Half-Life of Thymidine Kinase 1 in Serum Measured by ECL Dot Blot: A Potential Marker for Monitoring the Response to Surgery of Patients with Gastric Cancer

The International Journal of Biological Markers, 2002
Thymidine kinase 1 in serum (STK1) of patients with gastric cancer was determined by two methods: ECL dot blot and radioactivity assay. Both measurements showed significantly different values for preoperative STK1 and healthy STK1 (p=0.012 for ECL dot ...
L. Zou, P.-G. Zhang, S. Zou, Y. Li, Q. He Ph.D.   +4 more
doaj   +1 more source

A comparative study of replicative properties of antitumor recombinant vaccinia viruses on human glioblastoma cell culture U87 and monkey kidney cell culture CV-1

Вавиловский журнал генетики и селекции, 2017
In the world of today, virotherapy is one of the rapidly developing areas in the treatment of cancer, and its advantage is selective destruction of cancer cells with minimizing the destructive effect on normal cells of the body. A promising basis for the
R. A. Maksyutov, I. V. Kolosova, T. V. Tregubchak, I. A. Razumov, S. N. Shchelkunov   +4 more
doaj   +1 more source

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe, Vishal Satikuvar, Tanjia M. Syeda, Monica Cal, Pascal Mäser, Marcel Kaiser, Hachemi Kadri   +6 more
wiley   +1 more source