Results 181 to 190 of about 56,080 (273)

Mechanisms for the formation of thymine under astrophysical conditions and implications for the origin of life

, 2016
Partha P. Bera, Michel Nuevo, Christopher K. Materese, Scott A. Sandford, Timothy J. Lee   +4 more
openalex   +1 more source

A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium‐Embedded Mesoporous Silica and Chitosan Nanoparticles

ChemistryOpen, Volume 15, Issue 3, March 2026.
Herein, solvent extraction was selected for cetyltrimethylammonium bromide removal and the development of optimized Se‐embedded mesoporous silica nanoparticles, which were loaded with enzalutamide. Additionally, to improve the anticancer activity of Se@MSNPs‐Enz and curcumin bioavailability, curcumin‐loaded chitosan nanoparticles were prepared. This pH‐
Zahra Tavakoli, Khosro Khajeh, Bijan Ranjbar   +2 more
wiley   +1 more source

In silico conversion of ssRNA aptamers to ssDNA: molecular dynamics assessment of structural stability and conformational preservation. [PDF]

J Comput Aided Mol Des
Lorenti S, Alqualo NO, Moreira DC, Junior NN, Goulart VA.   +4 more
europepmc   +1 more source

Ions as Architects of DNA Nanostructures: Mechanisms, Simulations, and Technological Frontiers

Small Structures, Volume 7, Issue 3, March 2026.
Ions are not merely passive electrolytes but active regulators of DNA nanostructures. This review shows how ion valence, hydration, and specificity govern electrostatic screening, correlation, and confinement, enabling DNA origami, metallized DNA, nanopores, hydrogels, DNAzymes, molecular machines, and energy devices through integrated experimental and
Sergiy Perepelytsya, Dmytro Piatnytskyi, Tetiana Bubon, Narcis Cibotariu, Aatto Laaksonen, Francesca Mocci   +5 more
wiley   +1 more source

Transmembrane Transport of cAMP and AMP Using a Two Component Small Molecule Transport System. [PDF]

Angew Chem Int Ed Engl
Rathnaweera UMC, Sam O, Norvaisa K, Marshall SR, Weerakonda Arachchige RDS, Chvojka M, Valkenier H, Busschaert N.   +7 more
europepmc   +1 more source

Relaxation Dynamics of Hydrated Thymine, Thymidine, and Thymidine Monophosphate Probed by Liquid Jet Time-Resolved Photoelectron Spectroscopy

, 2019
Blake A. Erickson, Zachary N. Heim, Elisa Pieri, Erica Liu, Todd J. Martı́nez, Daniel M. Neumark   +5 more
openalex   +2 more sources

Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier, François‐Ludovic Sauvage, Christel Valencia‐Schmitt, Valérie Calco, Pascal Villa, Pierre Marquet, Roland Lawson   +6 more
wiley   +1 more source

DNA polymerase α-primase can function as a translesion DNA polymerase. [PDF]

Proc Natl Acad Sci U S A
Mayle R, Georgescu R, O'Donnell ME.
europepmc   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, Volume 59, Issue 3, March 2026.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Genome Sequences of Alatato and Audell, two Phages that infect <i>Arthrobacter globiformis</i> and have Different Life Cycles. [PDF]

MicroPubl Biol
Robinson SE, Stanford E, Abraham S, Aguilera R, Anantoji NS, Barillas M, Barstys R, Benson E, Boucher KR, Chacko AM, Chandrakanth N, Chau A, Chen A, Coleman J, Duc LT, Godfrey O, Hoang SN, Kethamreddy M, Kumar N, Le BN, Lin GT, Nguyen KB, Pandit M, Shah KD, Sharma M, Singh S, Smith J, Thomas LV, Varghese A, Wells I, Pollenz RS.   +30 more
europepmc   +1 more source