The impact of accumulating immune adaptation in circulating strains of HIV‐1
Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source
Electronic and Optical Sensitivity of Aluminum-Doped Boron Phosphide Monolayers for DNA Base Detection: A First-Principles Study. [PDF]
Ye S, Yeh CH.
europepmc +1 more source
ABSTRACT Background Hair mesotherapy is increasingly used in the management of androgenetic alopecia (AGA), yet standardized treatment protocols and controlled clinical data are limited. Aims This study aimed to evaluate the efficacy and safety of a mesotherapy formulation containing biomimetic peptides, vitamins, and micronutrients in patients with ...
Özlem Köse, Murat Borlu
wiley +1 more source
VERNALIZATION2 alters early tiller development in a facultative spring hexaploid bread wheat
Summary An extended period of cold exposure enables the process of vernalization in winter cereals and is important for the synchronised timing of the floral transition. The cereal‐specific floral repressor VERNALIZATION2 (VRN2) has an integral role in vernalization, yet this locus remains poorly characterised in facultative spring hexaploid wheat ...
Dominique Hirsz +5 more
wiley +1 more source
The mechanochemical activation of a pyrimidine dimer. [PDF]
Gao X +9 more
europepmc +1 more source
Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa +2 more
wiley +1 more source
Bead-Ejection Scenario in Electrospray Ionization of Multidomain Nucleic Acids. [PDF]
Ghosh D, Rosu F, Gabelica V.
europepmc +1 more source
DNA Scission by Non‐Histidine Amino‐Terminal Cu(II) and Ni(II) Binding‐Like Peptides
Non‐His amino‐terminal Cu(II) and Ni(II) binding (ATCUN)‐like peptides containing Ala and Asp instead of His form Cu(II)/Ni(II) complexes and induce oxidative plasmid DNA scission. The metallopeptides bind preferentially to AT‐rich DNA regions and promote nicking and linearization in the presence of Cu(II) and ascorbate. These findings demonstrate that
Lena K. Müller +7 more
wiley +1 more source
Mbd4 and MutSα protect cells from spontaneous deamination of 5-methylcytosine. [PDF]
Bilardi RA +5 more
europepmc +1 more source
Self‐Assembled Rhodium Nanoantennas for Single‐Protein UV SERS
The use of biofabrication (DNA origami) to prepare Rh nanocubes dimer enables the realization of a plasmonic platform for single‐molecule UV‐SERS. A reproducible, self‐assembly technique for nanofabrication, combined with UV spectroscopy extended the application of single molecule SERS to the UV spectral range.
Yanqiu Zou +14 more
wiley +1 more source

