Results 41 to 50 of about 5,476 (161)

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Impact of Letermovir on Voriconazole Concentrations in Lung Transplant Patients

Transplant Infectious Disease, EarlyView.
Concomitant letermovir was associated with lower voriconazole exposure and reduced attainment of commonly used efficacy thresholds in lung transplant recipients. Routine therapeutic drug monitoring after letermovir initiation is recommended, and empiric voriconazole dose escalation may be needed to avoid subtherapeutic exposure. ABSTRACT Background The
Leah Georgiades, Sunish Shah, Erin K. McCreary, Fernanda Silveira, Raman Venkataramanan, Vignesh Vasudevan, Ryan M. Rivosecchi   +6 more
wiley   +1 more source

Five‐Year Outcomes and Clinicopathological Correlations of Kidney Transplants From Deceased Donors With Diabetes

Clinical Transplantation, Volume 40, Issue 10, October 2026.
ABSTRACT Background Kidneys from deceased donors with diabetes mellitus are refused because diabetes is considered a marker of lower organ quality. We evaluated 5‐year outcomes according to donor‐recipient diabetes status and, secondarily, the prognostic value of pre‐implantation histopathological findings among accepted diabetic donor kidneys ...
Marina Colella‐Santos, Pedro Henrique Pepato, Henrique Machado de Sousa Proença, Luiz Antonio Ribeiro de Moura, José Medina‐Pestana, Renato Demarchi Foresto, Lúcio Requião‐Moura   +6 more
wiley   +1 more source

Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath [PDF]

, 2005
BACKGROUND: Multiple drug immunosuppression has allowed the near elimination of rejection, but without commensurate improvements in longterm graft survival and at the cost of quality of life.
Metes, D, Bass, DC, Basu, A, Zeevi, A, Starzl, TE, Girnita, A, Demetris, AJ, Marcos, A, Randhawa, P, Ness, R, Shapiro, R, Tan, H, Kahn, A, Fung, JJ, Gray, E, Murase, N   +15 more
core   +1 more source

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

Immunology, Volume 179, Issue 2, Page 269-286, October 2026.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu, Fırat Demircan, Başak Aru, Süheyla Apaydın, Abdullah Demir, Rabia Tığlı, Gürkan Tellioğlu, Ali Osman Gürol, Gülderen Yanıkkaya Demirel   +8 more
wiley   +1 more source

Predictive Value of HLA‐Derived T‐Cell Epitope and B‐Cell Epitope Matching Algorithms for Pancreas Transplant Outcomes

Clinical Transplantation, Volume 40, Issue 9, September 2026.
ABSTRACT Background Donor/recipient HLA molecular mismatches are predictive of kidney transplant outcomes. Their role in pancreas transplantation has not been well studied. Methods We conducted a retrospective cohort study in 281 pancreas (± kidney) transplant recipients during 2000–2018, followed for average 53.8 months.
Zakieh Zare, Matthias Niemann, Kasra Shirini, Ian Booth, Bethany Dale, Richard Ugarte, Silke V. Niederhaus, Cinthia B. Drachenberg, Abdolreza Haririan   +8 more
wiley   +1 more source

Economics of the antithymocyte globulins Thymoglobulin® and Atgam® in the treatment of acute renal transplant rejection

, 2000
Objective: To evaluate the economic implications for transplant centres, Medicare and society of treatment of corticosteroid-resistant Banff Grades I, II and III acute kidney transplant rejection with the antithymocyte globulins Thymoglobulin® or Atgam®.
Schroeder, Timothy, Schnitzler, Mark A, Woodward, Robert, Lowell, Jeffrey A, Singer, Gary G, Brennan, Daniel C, Amir, Leah   +6 more
core   +1 more source

Initial Experience with Grafalon as Induction Agent in Kidney Transplantation [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Renal transplantation is ideal modality of Renal Replacement Therapy (RRT) as it is cost effective and associated with quality of life.
Divyesh Engineer, Himanshu Patel, Vivek Kute, Pankaj Shah   +3 more
doaj   +1 more source

Thai Transplant Care Practice Guideline on Immunosuppressive Therapy for Adult Kidney Transplantation

Nephrology, Volume 31, Issue S2, September 2026.
ABSTRACT The Thai Transplantation Society developed these clinical practice guidelines to establish a comprehensive standard for immunosuppressive therapy in adult kidney transplantation. While rooted in evidence‐based medicine, the objective of this document extends beyond local application, serving as a practical model for low‐to‐middle‐income ...
Suwasin Udomkarnjananun, Napun Sutharattanapong, Nuttasith Larpparisuth, Korntip Phonphok, Tanun Ngamvichchukorn, Peenida Skulratanasak, Pitchamon Inkong, Suwikran Wongpraphairot, Opas Traitanon, Piyavadee Homkrailas, Kajohnsak Noppakun, Natavudh Townamchai, on behalf of Thai Transplantation Society   +12 more
wiley   +1 more source

Correlation of histology to clinical rejection reversal: A Thymoglobulin Multicenter Trial report [PDF]

, 1999
Correlation of histology to rejection reversal: A Thymoglobulin Multicenter Trial reportBackgroundHistology may provide a link between clinical response to antirejection therapy and graft function. In a subset of centers, renal biopsy was a secondary end
Meyer, Jayne, Schroeder, Timothy J., Tesi, Raymond J., Gaber, Lillian W., Moore, Linda W., Gaber, A. Osama   +5 more
core   +1 more source