Results 81 to 90 of about 5,476 (161)

Anti-Thymocyte Globulin (Thymoglobulin), Tacrolimus, and Sirolimus as Acute Graft-versus-Host Disease Prophylaxis for Unrelated Hematopoietic Stem Cell Transplantation [PDF]

, 2012
Acute graft-versus-host disease (aGVHD) is a major cause of morbidity and mortality in patients undergoing unrelated hematopoietic stem cell transplantation.
Alice Mitchell, Daryn Smith, Al-Kadhimi, Zaid, Joseph Uberti, Lum, Lawrence, Uberti, Joseph, Abhinav Deol, Wei Chen, Gul, Zartash, Forman, Stephen, Lois Ayash, Deol, Abhinav, Stephen Forman, Muneer Abidi, Ratanatharathorn, Voravit, Rodriguez, Roberto, Lawrence Lum, Zaid Al-Kadhimi, Voravit Ratanatharathorn, Chen, Wei, Abidi, Muneer, Zartash Gul, Mitchell, Alice, Roberto Rodriguez, Smith, Daryn, Ayash, Lois   +25 more
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The effect of low and ultra-low dosages Thymoglobulin on peripheral T, B and NK cells in kidney transplant recipients

, 2012
Introduction: Rabbit Anti-Thymocyte Globulin (r-ATG) is a polyclonal antibody preparation, used to prevent and treat acute rejection episodes after organ transplantation.
Cadogan, M, Kraaijeveld, Rens, Weimar, Willem, Kho, Marcia; id_orcid, Bouvy, Anne, Kho, Marcia, Baan, Carla   +6 more
core   +1 more source

Choice of Immunosuppression Influences Cytomegalovirus DNAemia in Cynomolgus Monkey () Islet Allograft Recipients

Cell Transplantation, 2010
This retrospective study reviews the results of our experience with the occurrence of CMV DNAemia in islet cell transplanted cynomolgus monkeys subjected to different immunosuppressive protocols, including induction treatment with thymoglobulin (TMG ...
Dongmei Han Ph.D., Dora M. Berman, Melissa Willman, Peter Buchwald, Daniel Rothen, Norman M. Kenyon, Norma S. Kenyon   +6 more
doaj   +1 more source

Thymoglobulin reduces regulatory T cell specific forkhead box P3 (FOXP3) transcripts in kidney transplant recipients

, 2022
BackgroundThe expression of the forkhead box P3 (FOXP3) protein is essential for the differentiation of T regulatory cells, which are major regulators of immune tolerance and immunologic activity.
Saleh, Qais Waleed, Tepel, Martin; id_orcid, Nagarajah, Subagini; id_orcid, Rasmussen, Marianne   +3 more
core   +1 more source

Short-course thymoglobulin induction and steroid-free immunosuppressive regimen in renal transplantation

, 2009
Purpose: Optimal induction and maintenance immunosuppressive therapies in renal transplantation are still a matter of debate.Chronic corticosteroid usage is a major cause of morbidity but steroid-free immunosuppression (SF) can result in unacceptably ...
Martin, P.Y., Venetz, J.P., Vallotton, L., Pascual, M., Hadaya, K., Ponte, B., Buhler, L.   +6 more
core   +1 more source

Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transfer

, 2019
The effect of anti-thymocyte globulin (ATG) on the outcome of hematopoietic stem cell transplantation (SCT) is dependent on formulation, dose and exposure. However, ATG levels are not routinely measured and therapeutic levels are not well defined.
Cameron I. Curley, Geoffrey R. Hill, Midori Nakagaki, Siok-Keen Tey, Curley, Cameron I., Kari Mudie, Ping Zhang, Nakagaki, Midori, Mudie, Kari, Jason A. Roberts, Tey, Siok-Keen, Zhang, Ping, Hill, Geoffrey R., Roberts, Jason A.   +13 more
core   +1 more source

Perioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation

, 2015
Aim: To describe our single-centre experience in liver transplantation (LT) with the infusion of high perioperative thymoglobulin doses. The optimal dosage and timing of thymoglobulin(®) [antithymocyte globulin (ATG)] administration during LT remains ...
Begliomini, Bruno, Preziosi, Giuseppe, Rompianesi, Gianluca, De Pietri, Lesley, Serra, Valentina   +4 more
core   +1 more source

Risk factors for hemorrhagic cystitis in children undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis

BMC Pediatrics
Background The risk factors for hemorrhagic cystitis (HC) in children undergoing hematopoietic stem cell transplantation (HSCT) are unclear. Therefore, we conducted this systematic review and meta-analysis to investigate the risk factors for HC in ...
Senlin Zhang, Minyuan Liu, Qingwei Wang, Shuran Wang, Xin Liu, Bohan Li, Jie Li, Junjie Fan, Shaoyan Hu   +8 more
doaj   +1 more source

Reduced toxicity matched sibling bone marrow transplant results in excellent outcomes for severe congenital neutropenia

Frontiers in Immunology
Severe congenital neutropenia (SCN) is caused by germline mutations, most commonly in ELANE, impacting neutrophil maturation and leading to high risk of life-threatening infections.
Joseph H. Oved, Nora M. Gibson, Nora M. Gibson, Kimberly Venella, Caitlin W. Elgarten, Lisa Wray, Julia T. Warren, Timothy S. Olson   +7 more
doaj   +1 more source

Thymoglobulin as an induction therapy: protection against ischemia and reperfusion injury [PDF]

Einstein (São Paulo), 2006
Objective: To asses graft function and survival after one year inpatients at high risk of acute tubular necrosis (ATN) and to definethe impact of this lesion on allograft function in patients whoutilized an induction protocol with Thymoglobulin (Thymo ...
Lúcio Roberto Requião Moura, Maurício Galvão Pereira, Marcelino Durão, Eduardo José Tonato, Ana Cristina Carvalho Matos, Eric Roger Wroclawski, Alvaro Pacheco-Silva   +6 more
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